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Literature summary extracted from

  • Bulos, B.A.; Thomas, B.J.; Sacktor, B.
    Calcium inhibition of the NAD+-linked isocitrate dehydrogenase from blowfly flight muscle mitochondria (1984), J. Biol. Chem., 259, 10232-10237.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.41 Ca2+
-
 Phormia regina
1.1.1.41 Mg2+ free form Phormia regina

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.1.1.41 Mg2+ required, active substrate is Mg-DL-isocitrate chelate Phormia regina
1.1.1.41 Mg2+ free form inhibits Phormia regina

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.41 isocitrate + NAD+ Phormia regina
-
 2-oxoglutarate + CO2 + NADH + H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.41 Phormia regina
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.41
-
 Phormia regina

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.41 muscle flight muscle Phormia regina
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.41 isocitrate + NAD+
-
 Phormia regina 2-oxoglutarate + CO2 + NADH + H+
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.41 NAD+
-
 Phormia regina