Literature summary extracted from

Vernon, C.M.; Hsu, R.Y.
Pigeon liver malic enzyme: involvement of an arginyl residue at the binding site for malate and its analogs (1983), Arch. Biochem. Biophys., 225, 296-305.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.1.1.40	2,3-Butanedione	pseudo-first-order loss of oxidative decarboxylase activity	Pigeon
1.1.1.40	Phenylglyoxal	pseudo-first-order loss of oxidative decarboxylase activity	Pigeon

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.1.1.40	Pigeon	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.1.1.40	liver	-	Pigeon	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.1.1.40	(S)-malate + NADP+	Arg residue is involved in the binding of C-1 carboxyl group of malate	Pigeon	pyruvate + CO2 + NADPH	-	r

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.1.1.40	NADP+	cofactor	Pigeon

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Release 2023.1 (January 2023)