EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.38 | fumarate | 0.7 mM, 2.1fold activation | Ascaris suum |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.38 | 2-methylbutanoate | 5.22 mM, competitive inhibitor, 60% inhibition at pH 7.5, 54% inhibition at pH 7.0 | Ascaris suum | |
1.1.1.38 | 2-methylpentanoate | 5.22 mM, competitive inhibitor, 45% inhibition at pH 7.5, 40% inhibition at pH 7.0 | Ascaris suum | |
1.1.1.38 | oxaloacetate | 1 mM, 80% inhibition at pH 7.5, 50% inhibition at pH 7.0 | Ascaris suum | |
1.1.1.38 | tiglic acid | 5.22 mM, competitive inhibitor, 58% inhibition at pH 7.5, 52% inhibition at pH 7.0 | Ascaris suum |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.1.1.38 | 0.06 | - |
NAD+ | at pH 6.5, 7.0 and 7.5 | Ascaris suum |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.1.1.38 | mitochondrion | - |
Ascaris suum | 5739 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.38 | (S)-malate + NAD+ | Ascaris suum | - |
CO2 + pyruvate + NADH | - |
? | |
1.1.1.38 | Oxaloacetate | Ascaris suum | - |
CO2 + pyruvate | - |
ir |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.1.38 | Ascaris suum | - |
parasitic roundwurm | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.38 | (S)-malate + NAD+ | - |
Ascaris suum | CO2 + pyruvate + NADH | - |
? | |
1.1.1.38 | (S)-malate + NAD+ | - |
Ascaris suum | CO2 + pyruvate + NADH | - |
r | |
1.1.1.38 | Oxaloacetate | - |
Ascaris suum | CO2 + pyruvate | - |
ir |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.38 | NAD+ | - |
Ascaris suum |