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Literature summary extracted from

  • Teague, W.M.; Henney, H.R.
    Physical properties and chemical compositions of cytoplasmic and mitochondrial malate dehydrogenase from Physarum polycephalum (1976), Biochim. Biophys. Acta, 434, 118-125.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.1.37 mitochondrion
-
 Sus scrofa 5739
-
1.1.1.37 mitochondrion
-
 Bos taurus 5739
-
1.1.1.37 mitochondrion
-
 Physarum polycephalum 5739
-
1.1.1.37 mitochondrion
-
 Gallus sp. 5739
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.37 35600
-
 2 * 35600, cytoplasmic form, SDS-PAGE Physarum polycephalum
1.1.1.37 37000
-
 2 * 37000, mitochondrial form, SDS-PAGE Physarum polycephalum
1.1.1.37 69500
-
 both isoenzymes, sedimentation equilibrium Physarum polycephalum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.37 malate + NAD+ Sus scrofa
-
 oxaloacetate + NADH + H+
-
 r
1.1.1.37 malate + NAD+ Bos taurus
-
 oxaloacetate + NADH + H+
-
 r
1.1.1.37 malate + NAD+ Physarum polycephalum
-
 oxaloacetate + NADH + H+
-
 r
1.1.1.37 malate + NAD+ Gallus sp.
-
 oxaloacetate + NADH + H+
-
 r
1.1.1.37 malate + NAD+ Salmo sp.
-
 oxaloacetate + NADH + H+
-
 r
1.1.1.37 malate + NAD+ Penaeus aztecus
-
 oxaloacetate + NADH + H+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.37 Bos taurus
-
-
-
1.1.1.37 Gallus sp.
-
 chicken
-
1.1.1.37 Penaeus aztecus
-
 brown shrimp
-
1.1.1.37 Physarum polycephalum
-
-
-
1.1.1.37 Salmo sp.
-
 salmonid fish
-
1.1.1.37 Sus scrofa
-
 pig
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.37
-
 Physarum polycephalum

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.37 heart
-
 Sus scrofa
-
1.1.1.37 heart
-
 Bos taurus
-
1.1.1.37 heart
-
 Gallus sp.
-
1.1.1.37 heart
-
 Salmo sp.
-
1.1.1.37 kidney
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.37 810
-
 cytoplasmic isoenzyme Physarum polycephalum
1.1.1.37 1020
-
 mitochondrial isoenzyme Physarum polycephalum

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.37 (S)-malate + NAD+
-
 Sus scrofa oxaloacetate + NADH + H+
-
 r
1.1.1.37 (S)-malate + NAD+
-
 Bos taurus oxaloacetate + NADH + H+
-
 r
1.1.1.37 (S)-malate + NAD+
-
 Physarum polycephalum oxaloacetate + NADH + H+
-
 r
1.1.1.37 (S)-malate + NAD+
-
 Gallus sp. oxaloacetate + NADH + H+
-
 r
1.1.1.37 (S)-malate + NAD+
-
 Salmo sp. oxaloacetate + NADH + H+
-
 r
1.1.1.37 (S)-malate + NAD+
-
 Penaeus aztecus oxaloacetate + NADH + H+
-
 r
1.1.1.37 malate + NAD+
-
 Sus scrofa oxaloacetate + NADH + H+
-
 r
1.1.1.37 malate + NAD+
-
 Bos taurus oxaloacetate + NADH + H+
-
 r
1.1.1.37 malate + NAD+
-
 Physarum polycephalum oxaloacetate + NADH + H+
-
 r
1.1.1.37 malate + NAD+
-
 Gallus sp. oxaloacetate + NADH + H+
-
 r
1.1.1.37 malate + NAD+
-
 Salmo sp. oxaloacetate + NADH + H+
-
 r
1.1.1.37 malate + NAD+
-
 Penaeus aztecus oxaloacetate + NADH + H+
-
 r
1.1.1.37 oxaloacetate + NADH
-
 Sus scrofa L-malate + NAD+
-
 r
1.1.1.37 oxaloacetate + NADH
-
 Bos taurus L-malate + NAD+
-
 r
1.1.1.37 oxaloacetate + NADH
-
 Physarum polycephalum L-malate + NAD+
-
 r
1.1.1.37 oxaloacetate + NADH
-
 Gallus sp. L-malate + NAD+
-
 r
1.1.1.37 oxaloacetate + NADH
-
 Salmo sp. L-malate + NAD+
-
 r
1.1.1.37 oxaloacetate + NADH
-
 Penaeus aztecus L-malate + NAD+
-
 r

Subunits

EC Number Subunits Comment Organism
1.1.1.37 dimer
-
 Sus scrofa
1.1.1.37 dimer
-
 Bos taurus
1.1.1.37 dimer 2 * 35600, cytoplasmic form, SDS-PAGE Physarum polycephalum
1.1.1.37 dimer 2 * 37000, mitochondrial form, SDS-PAGE Physarum polycephalum