Literature summary extracted from

Goetz, F.; Schleifer, K.H.
Biochemical properties and the physiological role of the fructose-1,6-bisphosphate activated L-lactate dehydrogenase from Staphylococcus epidermidis (1978), Eur. J. Biochem., 90, 555-561.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
1.1.1.27	fructose 1,6-diphosphate	L-lactate dehydrogenase form which is activated by fructose 1,6-diphosphate	Staphylococcus epidermidis

General Stability

EC Number	General Stability	Organism
1.1.1.27	fructose-1,6-diphosphate is necessary to stabilize the tetrameric enzyme form	Staphylococcus epidermidis

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
1.1.1.27	36000	-	4 * 36000, SDS-PAGE	Staphylococcus epidermidis
1.1.1.27	130000	-	tetramer, sucrose density gradient centrifugation in presence of fructose 1,6-diphosphate and NADH	Staphylococcus epidermidis

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.1.1.27	Staphylococcus epidermidis	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.1.1.27	pyruvate + NADH + H+	-	Staphylococcus epidermidis	(S)-lactate + NAD+	-	ir

Subunits

EC Number	Subunits	Comment	Organism
1.1.1.27	tetramer	4 * 36000, SDS-PAGE	Staphylococcus epidermidis

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.1.1.27	NADH	coenzyme	Staphylococcus epidermidis

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Release 2023.1 (January 2023)