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Literature summary extracted from

  • Bogin, O.; Peretz, M.; Burstein, Y.
    Thermoanaerobacter brockii alcohol dehydrogenase: characterization of the active site metal and its ligand amino acids (1997), Protein Sci., 6, 450-458.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.2 gene coding for TBADH cloned and overexpressed in Escherichia coli Thermoanaerobacter brockii

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
1.1.1.2
-
 Homo sapiens
1.1.1.2
-
 Thermoanaerobacter brockii
1.1.1.2
-
 Equus sp.

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.2 7
-
 2-butanol r-TBADH, wild-type, mutant D150C-TBADH Thermoanaerobacter brockii
1.1.1.2 7.17
-
 2-butanol mutant H59Q-TBADH Thermoanaerobacter brockii
1.1.1.2 8.45
-
 Cyclopentanol r-TBADH, wild-type Thermoanaerobacter brockii
1.1.1.2 8.7
-
 Cyclopentanol mutant H59Q-TBADH Thermoanaerobacter brockii
1.1.1.2 9.2
-
 2-butanol mutant C37A-TBADH Thermoanaerobacter brockii
1.1.1.2 16.71
-
 Cyclopentanol mutant D150C-TBADH Thermoanaerobacter brockii
1.1.1.2 19.33
-
 Cyclopentanol mutant C37S-TBADH Thermoanaerobacter brockii

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.2 Equus sp.
-
 horse
-
1.1.1.2 Homo sapiens
-
 human
-
1.1.1.2 Saccharomyces cerevisiae
-
 yeast
-
1.1.1.2 Thermoanaerobacter brockii
-
 formely Thermoanaerobium brockii
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.2
-
 Thermoanaerobacter brockii

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.2 liver
-
 Homo sapiens
-
1.1.1.2 liver
-
 Equus sp.
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.2 cyclopentanol + NADP+
-
 Thermoanaerobacter brockii cyclopentanal + NADPH
-
 r

Subunits

EC Number Subunits Comment Organism
1.1.1.2 tetramer
-
 Thermoanaerobacter brockii

Synonyms

EC Number Synonyms Comment Organism
1.1.1.2 TBADH
-
 Thermoanaerobacter brockii