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Literature summary extracted from

  • Bublitz, C.; Lehninger, A.L.
    Ascorbic acid synthesis in animal tissue I. TPN-L-gulonate dehydrogenase (1963), Methods Enzymol., 6, 334-337.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.19 p-chloromercuribenzoate
-
 Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.19 D-glucuronate + NADPH Sus scrofa formation of ascorbic acid L-gulonate + NADP+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.19 Sus scrofa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.19
-
 Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.19 kidney
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.19 additional information
-
-
 Sus scrofa

Storage Stability

EC Number Storage Stability Organism
1.1.1.19 -5°C, 2 weeks Sus scrofa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.19 D-galacturonate + NADPH
-
 Sus scrofa ?
-
 r
1.1.1.19 D-glucuronate + NADPH formation of ascorbic acid Sus scrofa L-gulonate + NADP+
-
 ?
1.1.1.19 L-gulonate + NADP+
-
 Sus scrofa D-glucuronate + NADPH
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.19 8.6 9.3
-
 Sus scrofa

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.19 NADPH
-
 Sus scrofa