Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Minskoff, S.A.; Racenis, P.V.; Granger, J.; Larkins, L.; Hajra, A.K.; Greenberg, M.L.
    Regulation of phosphatidic acid biosynthetic enzymes in Saccharomyces cerevisiae (1994), J. Lipid Res., 35, 2254-2262.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.1.1.101 dihydroxyacetone activation, used as carbon source in wild type cell cultures, greater activity compared to activity in glucose-grown cells Saccharomyces cerevisiae
1.1.1.101 ethanol activation, used as nonfermentable carbon source in wild type and tpa1 mutant cell cultures, greater activity compared to activity in glucose-grown cells Saccharomyces cerevisiae
1.1.1.101 glycerol activation, used as nonfermentable carbon source in wild type cell cultures, greater activity compared to activity in glucose-grown cells Saccharomyces cerevisiae
1.1.1.101 glycerol/ethanol activation, used as nonfermentable carbon source in wild type cell cultures, greater activity compared to activity in glucose-grown cells Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.101 acyldihydroxyacetone phosphate + NADPH Saccharomyces cerevisiae acyldihydroxyacetone phosphate pathway 1-acyl-sn-glycerol 3-phosphate + NADP+
-
 ?
1.1.1.101 acyldihydroxyacetone phosphate + NADPH Saccharomyces cerevisiae reaction in non-ether lipids biosynthesis 1-acyl-sn-glycerol 3-phosphate + NADP+
-
 ?
1.1.1.101 acyldihydroxyacetone phosphate + NADPH Saccharomyces cerevisiae tpa1 acyldihydroxyacetone phosphate pathway 1-acyl-sn-glycerol 3-phosphate + NADP+
-
 ?
1.1.1.101 acyldihydroxyacetone phosphate + NADPH Saccharomyces cerevisiae tpa1 reaction in non-ether lipids biosynthesis 1-acyl-sn-glycerol 3-phosphate + NADP+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.101 Saccharomyces cerevisiae
-
 tpa1 mutant strain
-
1.1.1.101 Saccharomyces cerevisiae
-
 wild-type strain
-
1.1.1.101 Saccharomyces cerevisiae tpa1
-
 tpa1 mutant strain
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.101 0.00393
-
 glucose grown cells Saccharomyces cerevisiae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.101 acyldihydroxyacetone phosphate + NADPH
-
 Saccharomyces cerevisiae 1-acyl-sn-glycerol 3-phosphate + NADP+ i.e. lysophosphatidic acid ?
1.1.1.101 acyldihydroxyacetone phosphate + NADPH acyldihydroxyacetone phosphate pathway Saccharomyces cerevisiae 1-acyl-sn-glycerol 3-phosphate + NADP+
-
 ?
1.1.1.101 acyldihydroxyacetone phosphate + NADPH reaction in non-ether lipids biosynthesis Saccharomyces cerevisiae 1-acyl-sn-glycerol 3-phosphate + NADP+
-
 ?
1.1.1.101 acyldihydroxyacetone phosphate + NADPH
-
 Saccharomyces cerevisiae tpa1 1-acyl-sn-glycerol 3-phosphate + NADP+ i.e. lysophosphatidic acid ?
1.1.1.101 acyldihydroxyacetone phosphate + NADPH acyldihydroxyacetone phosphate pathway Saccharomyces cerevisiae tpa1 1-acyl-sn-glycerol 3-phosphate + NADP+
-
 ?
1.1.1.101 acyldihydroxyacetone phosphate + NADPH reaction in non-ether lipids biosynthesis Saccharomyces cerevisiae tpa1 1-acyl-sn-glycerol 3-phosphate + NADP+
-
 ?
1.1.1.101 hexadecyldihydroxyacetone phosphate + NADPH
-
 Saccharomyces cerevisiae 1-hexadecyl-sn-glycerol 3-phosphate + NADP+
-
 ?
1.1.1.101 hexadecyldihydroxyacetone phosphate + NADPH
-
 Saccharomyces cerevisiae tpa1 1-hexadecyl-sn-glycerol 3-phosphate + NADP+
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.101 NADPH hydrogen from B-side of nicotinamide ring is transferred to reduce keto substrates Saccharomyces cerevisiae