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Literature summary extracted from

  • Martin, K.O.; Oh, S.W.; Lee, H.J.; Monder, C.
    Studies on 21-3H-labeled corticosteroids: evidence for isomerization of the ketol side chain of 11-deoxycorticosterone by a hamster liver (1977), Biochemistry, 16, 3803-3809.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.3.1.21 1,10-phenanthroline
-
 Mesocricetus auratus
5.3.1.21 Ag+ weak Mesocricetus auratus
5.3.1.21 Cu2+ weak Mesocricetus auratus
5.3.1.21 EDTA reactivation by Co2+, Fe2+, Mo5+ Mesocricetus auratus
5.3.1.21 Hg2+ weak Mesocricetus auratus
5.3.1.21 PCMB weak Mesocricetus auratus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
5.3.1.21 0.0038
-
 11-deoxycorticosterone
-
 Mesocricetus auratus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
5.3.1.21 Co2+ stimulates Mesocricetus auratus
5.3.1.21 Fe2+ stimulates Mesocricetus auratus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
5.3.1.21 389000
-
 gel filtration Mesocricetus auratus

Organism

EC Number Organism UniProt Comment Textmining
5.3.1.21 Mesocricetus auratus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
5.3.1.21
-
 Mesocricetus auratus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.3.1.21 liver
-
 Mesocricetus auratus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
5.3.1.21 additional information
-
-
 Mesocricetus auratus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.3.1.21 11-Deoxycorticosterone
-
 Mesocricetus auratus 20-Hydroxy-3-oxopregn-4-en-21-al
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
5.3.1.21 8 9
-
 Mesocricetus auratus