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Literature summary extracted from

  • Kobayashi, M.; Ohara-Nemoto, Y.; Kaneko, M.; Hayakawa, H.; Sekiguchi, M.; Yamamoto, K.
    Potential of Escherichia coli GTP cyclohydrolase II for hydrolyzing 8-oxo-dGTP, a mutagenic substrate for DNA synthesis (1988), J. Biol. Chem., 273, 26394-26399.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.5.4.25 0.21
-
 8-oxo-GTP
-
 Escherichia coli
3.5.4.25 0.29
-
 GTP
-
 Escherichia coli
3.5.4.25 0.3
-
 8-oxo-dGTP
-
 Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.4.25 GTP + H2O Escherichia coli
-
 formate + 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + diphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.5.4.25 Escherichia coli
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.5.4.25
-
 Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.4.25 8-oxo-dGTP + H2O
-
 Escherichia coli ?
-
 ?
3.5.4.25 GTP + H2O
-
 Escherichia coli formate + 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + diphosphate
-
 ?