BRENDA - Enzyme Database

Identification, cloning, and expression of the Escherichia coli pyrazinamidase and nicotinamidase gene, pncA

Frothingham, R.; Meeker-OśConnell, W.A.; Talbot, E.A.S.; George, J.W.; Kreuzer K.N.; Antimicrob. Agents Chemother. 40, 1426-1431 (1996)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Cloned (Commentary)
Organism
3.5.1.19
a single enzyme accounts for both pyrazinamidase activity and nicotinamidase activity
Escherichia coli
Organism
EC Number
Organism
UniProt
Commentary
Textmining
3.5.1.19
Escherichia coli
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
3.5.1.19
nicotinamide + H2O
-
246582
Escherichia coli
nicotinate + NH3
-
-
-
?
3.5.1.19
pyrazinamide + H2O
-
246582
Escherichia coli
pyrazinoic acid + NH3
-
246582
Escherichia coli
?
Synonyms
EC Number
Synonyms
Commentary
Organism
3.5.1.19
PZAase
a single enzyme accounts for both pyrazinamidase activity and nicotinamidase activity
Escherichia coli
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
3.5.1.19
a single enzyme accounts for both pyrazinamidase activity and nicotinamidase activity
Escherichia coli
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
3.5.1.19
nicotinamide + H2O
-
246582
Escherichia coli
nicotinate + NH3
-
-
-
?
3.5.1.19
pyrazinamide + H2O
-
246582
Escherichia coli
pyrazinoic acid + NH3
-
246582
Escherichia coli
?