EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.1.1.77 | Triton X-100 | required | Homo sapiens |
EC Number | Application | Comment | Organism |
---|---|---|---|
3.1.1.77 | analysis | potential use in studies of LPS structure and bioactivity | Homo sapiens |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.1.77 | 0.00026 | - |
long chain lipopolysaccharide | - |
Homo sapiens | |
3.1.1.77 | 0.00031 | - |
medium chain lipopolysaccharide | - |
Homo sapiens | |
3.1.1.77 | 0.00032 | - |
short chain lipopolysaccharide | - |
Homo sapiens |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.1.1.77 | Ca2+ | CaCl2 enhances activity at pH 4.8 by 1.5-2 fold | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.1.77 | 3-(acyloxy)acyl group of bacterial toxin | Homo sapiens | detoxification of LPS | 3-hydroxyacyl group of bacterial toxin + a fatty acid | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.1.77 | Homo sapiens | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.1.1.77 | - |
Homo sapiens |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.1.77 | HL-60 cell | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.1.77 | 3-(acyloxy)acyl group of bacterial toxin | detoxification of LPS | Homo sapiens | 3-hydroxyacyl group of bacterial toxin + a fatty acid | - |
? | |
3.1.1.77 | 3-(acyloxy)acyl group of bacterial toxin + H2O | smooth LPS deacylated more slowly than rough LPS | Homo sapiens | 3-hydroxyacyl group of bacterial toxin + a fatty acid | palmitoleate released more slowly than myristate and laurate, 2-hydroxylaurate released more slowly than laurate | ? | |
3.1.1.77 | long chain lipopolysaccharide + H2O | - |
Homo sapiens | ? | - |
? | |
3.1.1.77 | medium chain lipopolysaccharide + H2O | - |
Homo sapiens | ? | - |
? | |
3.1.1.77 | short chain lipopolysaccharide + H2O | - |
Homo sapiens | ? | - |
? |