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Literature summary extracted from
- delta-Aminolevulinic acid dehydratase from shell gland and liver of Japanese quail, Coturnix coturnix japonica. I. Purification, properties and hormonal induction (1972), Biochim. Biophys. Acta, 279, 535-543.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.2.1.24 | iodoacetate | - |
Coturnix japonica |  |
| 4.2.1.24 | NEM | - |
Coturnix japonica | |
| 4.2.1.24 | PCMB | - |
Coturnix japonica | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 4.2.1.24 | 0.061 | - |
5-aminolevulinate | shell gland enzyme | Coturnix japonica | |
| 4.2.1.24 | 0.2 | - |
5-aminolevulinate | liver enzyme | Coturnix japonica | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.1.24 | 5-aminolevulinate | Coturnix japonica | induction by 17beta-estradiol of 5-aminolevulinate | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.2.1.24 | Coturnix japonica | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 4.2.1.24 | liver | - |
Coturnix japonica | - |
| 4.2.1.24 | shell gland | maximal activity before pigmentation of the egg shell | Coturnix japonica | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 4.2.1.24 | 6.98 | - |
shell gland enzyme | Coturnix japonica |
| 4.2.1.24 | 10.3 | - |
liver enzyme | Coturnix japonica |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.1.24 | 5-aminolevulinate | induction by 17beta-estradiol of 5-aminolevulinate | Coturnix japonica | ? | - |
? | |
| 4.2.1.24 | 5-aminolevulinate + 5-aminolevulinate | - |
Coturnix japonica | porphobilinogen + 2 H2O | - |
? | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 4.2.1.24 | 60 | - |
- |
Coturnix japonica |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.2.1.24 | 6.9 | 7.1 | - |
Coturnix japonica |
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