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Literature summary extracted from

  • Smigan, P.; Majernik, A.; Polak, P.; Hapala, I.; Greksak, M.
    The presence of H+ and Na+-translocating ATPases in Methanobacterium thermoautotrophicum and their possible function under alkaline conditions (1995), FEBS Lett., 371, 119-122.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
7.2.2.1 bafilomycin A1 stimulates ATP synthesis Methanothermobacter thermautotrophicus
7.2.2.1 Harmaline stimulates ATP synthesis Methanothermobacter thermautotrophicus

Application

EC Number Application Comment Organism
7.2.2.3 medicine ATP hydrolysis Methanothermobacter thermautotrophicus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
7.2.2.1 Na+ the enzyme has Na+-translocating activity Methanothermobacter thermautotrophicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
7.2.2.1 400000
-
 non-denaturing PAGE Methanothermobacter thermautotrophicus
7.2.2.3 400000
-
 PAGE Methanothermobacter thermautotrophicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.2.2.3 ATP + H2O + Na+/in Methanothermobacter thermautotrophicus
-
 ADP + phosphate + Na+/out
-
 r
7.2.2.3 ATP + H2O + Na+/in Methanothermobacter thermautotrophicus DELTAH
-
 ADP + phosphate + Na+/out
-
 r

Organism

EC Number Organism UniProt Comment Textmining
7.2.2.1 Methanothermobacter thermautotrophicus
-
-
-
7.2.2.1 Methanothermobacter thermautotrophicus DELTAH
-
-
-
7.2.2.3 Methanothermobacter thermautotrophicus
-
 strain delta H
-

Purification (Commentary)

EC Number Purification (Comment) Organism
7.2.2.3
-
 Methanothermobacter thermautotrophicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.2.2.1 ADP + phosphate Na+-translocating ATPase can work in the synthase mode under alkaline conditions Methanothermobacter thermautotrophicus ATP
-
 r
7.2.2.1 ADP + phosphate Na+-translocating ATPase can work in the synthase mode under alkaline conditions Methanothermobacter thermautotrophicus DELTAH ATP
-
 r
7.2.2.1 ATP + H2O Na+-translocating ATPase can work in the synthase mode under alkaline conditions Methanothermobacter thermautotrophicus ADP + phosphate
-
 r
7.2.2.1 ATP + H2O Na+-translocating ATPase can work in the synthase mode under alkaline conditions Methanothermobacter thermautotrophicus DELTAH ADP + phosphate
-
 r
7.2.2.3 ATP + H2O + Na+/in
-
 Methanothermobacter thermautotrophicus ADP + phosphate + Na+/out
-
 r
7.2.2.3 ATP + H2O + Na+/in
-
 Methanothermobacter thermautotrophicus DELTAH ADP + phosphate + Na+/out
-
 r

Synonyms

EC Number Synonyms Comment Organism
7.2.2.1 F1FO-ATPase
-
 Methanothermobacter thermautotrophicus