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Literature summary extracted from
- Influence of phosphorylation by protein kinase A on CFTR at the cell surface and endoplasmic reticulum (1999), Biochim. Biophys. Acta, 1461, 275-283.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.6.1.6 | glibenclamide | - |
Homo sapiens |  |
| 5.6.1.6 | Tolbutamide | - |
Homo sapiens | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 5.6.1.6 | additional information | - |
additional information | 35-40 mM Cl- | Homo sapiens |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.6.1.6 | Homo sapiens | - |
- |
- |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 5.6.1.6 | glycoprotein | - |
Homo sapiens |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.6.1.6 | ATP + H2O + closed Cl- channel | chloride channel | Homo sapiens | ADP + phosphate + open Cl- channel | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 5.6.1.6 | ? | x * 150000-170000, fully glycosylated DELTAF508-CFTR, SDS-PAGE | Homo sapiens |
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Release 2023.1 (January 2023)
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