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Literature summary extracted from

  • Capito, K.; Hansen, S.E.; Hedeskov, C.J.; Thams, D.
    Presence of ATP-pyrophosphohydrolase in mouse pancreatic islets (1986), Diabetes, 35, 1096-1100.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.6.1.8 3-isobutyl-1-methylxanthine activation in preincubation Mus musculus
3.6.1.8 cAMP weak activation Mus musculus
3.6.1.8 glucose activation in preincubation Mus musculus
3.6.1.8 NaF 20 mM Mus musculus
3.6.1.8 NaN3 10 mM Mus musculus
3.6.1.8 oleic acid
-
 Mus musculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.6.1.8 phosphatidylserine
-
 Mus musculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.6.1.8 0.076
-
 ATP in presence of ZnCl2 and CaCl2 Mus musculus
3.6.1.8 0.18
-
 ATP in presence of 2 mM ZnCl2 Mus musculus
3.6.1.8 0.2
-
 ATP without added metal ions Mus musculus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.6.1.8 Ba2+ no effect Mus musculus
3.6.1.8 Ca2+ required for activity Mus musculus
3.6.1.8 Co2+ activating Mus musculus
3.6.1.8 Mg2+ no effect Mus musculus
3.6.1.8 Mn2+ no effect Mus musculus
3.6.1.8 Sr2+ no effect Mus musculus
3.6.1.8 Zn2+ activating Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.6.1.8 ATP + H2O Mus musculus
-
 AMP + diphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.6.1.8 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.6.1.8 pancreatic islet
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.1.8 ATP + H2O
-
 Mus musculus AMP + diphosphate
-
 ?