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Literature summary extracted from

  • Lemmens, R.; Kupers, L.; Sevigny, J.; Beaudoin, A.R.; Grondin, G.; Kittel, A.; Waelkens, E.; Vanduffel, L.
    Purification, characterization, and localisation of an ATP diphosphohydrolase in porcine kidney (2000), Am. J. Physiol., 278, 978-988.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.6.1.5 EGTA
-
 Sus scrofa
3.6.1.5 NaN3
-
 Sus scrofa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.6.1.5 membrane ectonucleotidase/ectoenzyme Sus scrofa 16020
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.6.1.5 Ca2+ either Mg2+ or Ca2+ required for activity Sus scrofa
3.6.1.5 Ca2+ Ca2+ preferred to Mg2+ Sus scrofa
3.6.1.5 Mg2+ either Mg2+ or Ca2+ required for activity Sus scrofa

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.6.1.5 78000
-
 highly glycosylated, nominal weight of 57 kDa Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.6.1.5 ADP + H2O Sus scrofa
-
 AMP + phosphate
-
 ?
3.6.1.5 ATP + 2 H2O Sus scrofa
-
 AMP + 2 phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.6.1.5 Sus scrofa
-
 pig
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.6.1.5 glycoprotein highly glycosylated, nominal weight of 57 kDa Sus scrofa
3.6.1.5 glycoprotein N-linked oligosaccarides Sus scrofa

Purification (Commentary)

EC Number Purification (Comment) Organism
3.6.1.5
-
 Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.6.1.5 kidney cortex, detected by immunoblotting in blood vessel walls of glomerular and peritubular capillaries Sus scrofa
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.6.1.5 2.4
-
 ATP Sus scrofa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.1.5 ADP + H2O
-
 Sus scrofa AMP + phosphate
-
 ?
3.6.1.5 ATP + 2 H2O
-
 Sus scrofa AMP + 2 phosphate
-
 ?
3.6.1.5 CDP + H2O
-
 Sus scrofa CMP + phosphate
-
 ?
3.6.1.5 CTP + 2 H2O
-
 Sus scrofa CMP + 2 phosphate
-
 ?
3.6.1.5 GDP + H2O
-
 Sus scrofa GMP + phosphate
-
 ?
3.6.1.5 GTP + 2 H2O
-
 Sus scrofa GMP + 2 phosphate
-
 ?
3.6.1.5 IDP + H2O
-
 Sus scrofa IMP + phosphate
-
 ?
3.6.1.5 ITP + 2 H2O
-
 Sus scrofa IMP + 2 phosphate
-
 ?
3.6.1.5 additional information neglible hydrolysis of AMP Sus scrofa ?
-
 ?
3.6.1.5 TTP + 2 H2O
-
 Sus scrofa TMP + 2 phosphate
-
 ?
3.6.1.5 UDP + H2O
-
 Sus scrofa UMP + phosphate
-
 ?
3.6.1.5 UTP + 2 H2O
-
 Sus scrofa UMP + 2 phosphate
-
 ?