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Literature summary extracted from

  • Anderson, B.M.; Lang, C.A.
    Nicotinamide-adenin dinucleotide pyrophosphatase in the growing and aging mosquito (1966), Biochem. J., 101, 392-396.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.6.1.22 3-acetylpyridine 20% inhibition at conentration of 0.1 M Aedes aegypti

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.6.1.22 NAD+ + H2O Aedes aegypti
-
 NMN + AMP
-
 ir

Organism

EC Number Organism UniProt Comment Textmining
3.6.1.22 Aedes aegypti
-
 larval
-

Storage Stability

EC Number Storage Stability Organism
3.6.1.22 -20°C, storage of homogenates for several weeks, no loss of activity Aedes aegypti
3.6.1.22 37°C, 0.1 M Tris, pH 8.75, 150 min, no loss of activity Aedes aegypti

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.1.22 acetylpyridine adenine dinucleotide + H2O
-
 Aedes aegypti ?
-
 ?
3.6.1.22 NAD+ + H2O
-
 Aedes aegypti NMN + AMP
-
 ir
3.6.1.22 NADP+ + H2O
-
 Aedes aegypti NMN + adenosine 3',5'-diphosphate
-
 ?
3.6.1.22 thio-NAD+ + H2O
-
 Aedes aegypti ?
-
 ?
3.6.1.22 thio-NADP+ + H2O
-
 Aedes aegypti ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.6.1.22 nicotinamide adenine dinucleotide pyrophosphatase
-
-

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.6.1.22 50
-
 range 20-65°C in 5°C steps Aedes aegypti

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.6.1.22 100
-
 2 min at 100°C causes complete loss of activity Aedes aegypti

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.6.1.22 8.8
-
-
 Aedes aegypti

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.6.1.22 7.5 9.5 40% of maximum activity at pH 7.5, 60% of maximum activity at pH 9.5 Aedes aegypti