EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.5.4.12 | dCTP | activation, absolute requirement for dCTP | Mycoplasma mycoides |
EC Number | General Stability | Organism |
---|---|---|
3.5.4.12 | highly stable enzyme | Mycoplasma mycoides |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.5.4.12 | dTTP | allosteric inhibitor | Mycoplasma mycoides |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.5.4.12 | additional information | - |
additional information | preliminary kinetic studies and kinetic data | Mycoplasma mycoides | |
3.5.4.12 | 0.046 | - |
dCMP | - |
Mycoplasma mycoides |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.5.4.12 | dCMP + H2O | Mycoplasma mycoides | enzyme of pyrimidine deoxyribonucleotide metabolism, important for the synthesis of thymidine nucleotides from thymine. Enzyme could provide the major means of dUMP formation | dUMP + NH3 | - |
? | |
3.6.1.12 | dCTP + H2O | Mycoplasma mycoides | enzyme of salvage synthesis of pyrimidine deoxyribonucleotides | dCMP + diphosphate | - |
? | |
3.6.1.23 | dUTP + H2O | Mycoplasma mycoides | enzyme of pyrimidine deoxyribonucleotide metabolism | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.4.14 | Mycoplasma mycoides | - |
subsp. mycoides | - |
3.5.4.12 | Mycoplasma mycoides | - |
subsp. mycoides | - |
3.6.1.12 | Mycoplasma mycoides | - |
subsp. mycoides | - |
3.6.1.23 | Mycoplasma mycoides | - |
subsp. mycoides | - |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
3.5.4.12 | dCMP + H2O = dUMP + NH3 | regulation, allosteric end-product regulation | Mycoplasma mycoides | |
3.5.4.12 | dCMP + H2O = dUMP + NH3 | highly regulated allosteric enzyme | Mycoplasma mycoides |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.4.14 | ATP + CMP | - |
Mycoplasma mycoides | ADP + CDP | - |
? | |
2.7.4.14 | ATP + dCMP | no evidence for reversal of the reaction | Mycoplasma mycoides | ADP + dCDP | - |
? | |
2.7.4.14 | ATP + dCMP | no evidence for reversal of the reaction | Mycoplasma mycoides | ADP + dCDP | - |
ir | |
3.5.4.12 | dCMP + H2O | - |
Mycoplasma mycoides | dUMP + NH3 | - |
? | |
3.5.4.12 | dCMP + H2O | enzyme of pyrimidine deoxyribonucleotide metabolism, important for the synthesis of thymidine nucleotides from thymine. Enzyme could provide the major means of dUMP formation | Mycoplasma mycoides | dUMP + NH3 | - |
? | |
3.6.1.12 | dCTP + H2O | - |
Mycoplasma mycoides | dCMP + diphosphate | - |
? | |
3.6.1.12 | dCTP + H2O | enzyme of salvage synthesis of pyrimidine deoxyribonucleotides | Mycoplasma mycoides | dCMP + diphosphate | - |
? | |
3.6.1.23 | dUTP + H2O | - |
Mycoplasma mycoides | dUMP + diphosphate | - |
? | |
3.6.1.23 | dUTP + H2O | enzyme of pyrimidine deoxyribonucleotide metabolism | Mycoplasma mycoides | ? | - |
? |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.5.4.12 | 37 | - |
assay at | Mycoplasma mycoides |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.5.4.12 | 7.8 | - |
assay at | Mycoplasma mycoides |