BRENDA - Enzyme Database show

On the role of cytidine deaminase in cellular metabolism

Nygaard, P.; Adv. Exp. Med. Biol. 195B, 415-420 (1986)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
3.5.4.5
cytidine
-
Escherichia coli
3.5.4.5
cytidine
-
Salmonella enterica subsp. enterica serovar Typhimurium
3.5.4.5
uridine
-
Salmonella enterica subsp. enterica serovar Typhimurium
Application
EC Number
Application
Commentary
Organism
3.5.4.5
medicine
different effect of cytidine in blood cells from healthy donors and chronic lymphocytic and acute myeloblastic leukemia patients
Homo sapiens
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3.5.4.5
cytidine + H2O
Salmonella enterica subsp. enterica serovar Typhimurium
-
uridine + NH3
-
-
?
3.5.4.5
cytidine + H2O
Mus musculus
-
uridine + NH3
-
-
?
3.5.4.5
cytidine + H2O
Escherichia coli
-
uridine + NH3
-
-
?
3.5.4.5
cytidine + H2O
Homo sapiens
-
uridine + NH3
-
-
?
3.5.4.5
cytidine + H2O
Saccharomyces cerevisiae
-
uridine + NH3
-
-
?
3.5.4.5
cytidine + H2O
Ovis aries
-
uridine + NH3
-
-
?
3.5.4.5
cytidine + H2O
Zea mays
-
uridine + NH3
-
-
?
3.5.4.5
cytidine + H2O
Mus musculus BALB/c
-
uridine + NH3
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.5.4.5
Escherichia coli
-
-
-
3.5.4.5
Homo sapiens
-
hematopoietic cell lines; human
-
3.5.4.5
Mus musculus
-
BALB/c; mouse
-
3.5.4.5
Mus musculus BALB/c
-
BALB/c
-
3.5.4.5
no activity in Lactobacillus sp.
-
-
-
3.5.4.5
no activity in Moraxella sp.
-
-
-
3.5.4.5
no activity in Pseudomonas sp.
-
-
-
3.5.4.5
Ovis aries
-
-
-
3.5.4.5
Saccharomyces cerevisiae
-
-
-
3.5.4.5
Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-
3.5.4.5
Zea mays
-
corn
-
Purification (Commentary)
EC Number
Commentary
Organism
3.5.4.5
-
Saccharomyces cerevisiae
3.5.4.5
-
Zea mays
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
3.5.4.5
granulocyte
-
Homo sapiens
-
3.5.4.5
kidney
-
Homo sapiens
-
3.5.4.5
kidney
-
Mus musculus
-
3.5.4.5
leukocyte
-
Homo sapiens
-
3.5.4.5
liver
-
Ovis aries
-
3.5.4.5
liver
-
Mus musculus
-
3.5.4.5
liver
-
Homo sapiens
-
3.5.4.5
marrow
-
Homo sapiens
-
3.5.4.5
spleen
-
Mus musculus
-
3.5.4.5
spleen
-
Homo sapiens
-
3.5.4.5
thymocyte
-
Homo sapiens
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.5.4.5
5'-fluoro-5'-deoxycytidine + H2O
-
209659
Salmonella enterica subsp. enterica serovar Typhimurium
5'-fluoro-5'-deoxyuridine + NH3
-
-
-
?
3.5.4.5
5'-fluoro-5'-deoxycytidine + H2O
-
209659
Escherichia coli
5'-fluoro-5'-deoxyuridine + NH3
-
-
-
?
3.5.4.5
5-azacytidine + H2O
-
209659
Salmonella enterica subsp. enterica serovar Typhimurium
5-azauridine + NH3
-
-
-
?
3.5.4.5
5-azacytidine + H2O
-
209659
Escherichia coli
5-azauridine + NH3
-
-
-
?
3.5.4.5
5-azacytidine + H2O
-
209659
Homo sapiens
5-azauridine + NH3
-
-
-
?
3.5.4.5
cytidine + H2O
-
209659
Salmonella enterica subsp. enterica serovar Typhimurium
uridine + NH3
-
-
-
?
3.5.4.5
cytidine + H2O
-
209659
Mus musculus
uridine + NH3
-
-
-
?
3.5.4.5
cytidine + H2O
-
209659
Escherichia coli
uridine + NH3
-
-
-
?
3.5.4.5
cytidine + H2O
-
209659
Homo sapiens
uridine + NH3
-
-
-
?
3.5.4.5
cytidine + H2O
-
209659
Saccharomyces cerevisiae
uridine + NH3
-
-
-
?
3.5.4.5
cytidine + H2O
-
209659
Ovis aries
uridine + NH3
-
-
-
?
3.5.4.5
cytidine + H2O
-
209659
Zea mays
uridine + NH3
-
-
-
?
3.5.4.5
cytidine + H2O
-
209659
Mus musculus BALB/c
uridine + NH3
-
-
-
?
3.5.4.5
cytosine arabinoside + H2O
-
209659
Salmonella enterica subsp. enterica serovar Typhimurium
uridine arabinoside + NH3
-
-
-
?
3.5.4.5
cytosine arabinoside + H2O
-
209659
Mus musculus
uridine arabinoside + NH3
-
-
-
?
3.5.4.5
cytosine arabinoside + H2O
-
209659
Escherichia coli
uridine arabinoside + NH3
-
-
-
?
3.5.4.5
cytosine arabinoside + H2O
-
209659
Homo sapiens
uridine arabinoside + NH3
-
-
-
?
3.5.4.5
cytosine arabinoside + H2O
-
209659
Mus musculus BALB/c
uridine arabinoside + NH3
-
-
-
?
3.5.4.5
deoxycytidine + H2O
-
209659
Salmonella enterica subsp. enterica serovar Typhimurium
deoxyuridine + NH3
-
-
-
?
3.5.4.5
deoxycytidine + H2O
-
209659
Mus musculus
deoxyuridine + NH3
-
-
-
?
3.5.4.5
deoxycytidine + H2O
-
209659
Escherichia coli
deoxyuridine + NH3
-
-
-
?
3.5.4.5
deoxycytidine + H2O
-
209659
Homo sapiens
deoxyuridine + NH3
-
-
-
?
3.5.4.5
deoxycytidine + H2O
-
209659
Mus musculus BALB/c
deoxyuridine + NH3
-
-
-
?
3.5.4.5
additional information
cytosine and cytosine nucleotides are no substrates
209659
Salmonella enterica subsp. enterica serovar Typhimurium
?
-
-
-
-
3.5.4.5
additional information
cytosine and cytosine nucleotides are no substrates
209659
Escherichia coli
?
-
-
-
-
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
3.5.4.5
cytidine
-
Escherichia coli
3.5.4.5
cytidine
-
Salmonella enterica subsp. enterica serovar Typhimurium
3.5.4.5
uridine
-
Salmonella enterica subsp. enterica serovar Typhimurium
Application (protein specific)
EC Number
Application
Commentary
Organism
3.5.4.5
medicine
different effect of cytidine in blood cells from healthy donors and chronic lymphocytic and acute myeloblastic leukemia patients
Homo sapiens
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3.5.4.5
cytidine + H2O
Salmonella enterica subsp. enterica serovar Typhimurium
-
uridine + NH3
-
-
?
3.5.4.5
cytidine + H2O
Mus musculus
-
uridine + NH3
-
-
?
3.5.4.5
cytidine + H2O
Escherichia coli
-
uridine + NH3
-
-
?
3.5.4.5
cytidine + H2O
Homo sapiens
-
uridine + NH3
-
-
?
3.5.4.5
cytidine + H2O
Saccharomyces cerevisiae
-
uridine + NH3
-
-
?
3.5.4.5
cytidine + H2O
Ovis aries
-
uridine + NH3
-
-
?
3.5.4.5
cytidine + H2O
Zea mays
-
uridine + NH3
-
-
?
3.5.4.5
cytidine + H2O
Mus musculus BALB/c
-
uridine + NH3
-
-
?
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
3.5.4.5
-
Saccharomyces cerevisiae
3.5.4.5
-
Zea mays
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
3.5.4.5
granulocyte
-
Homo sapiens
-
3.5.4.5
kidney
-
Homo sapiens
-
3.5.4.5
kidney
-
Mus musculus
-
3.5.4.5
leukocyte
-
Homo sapiens
-
3.5.4.5
liver
-
Ovis aries
-
3.5.4.5
liver
-
Mus musculus
-
3.5.4.5
liver
-
Homo sapiens
-
3.5.4.5
marrow
-
Homo sapiens
-
3.5.4.5
spleen
-
Mus musculus
-
3.5.4.5
spleen
-
Homo sapiens
-
3.5.4.5
thymocyte
-
Homo sapiens
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.5.4.5
5'-fluoro-5'-deoxycytidine + H2O
-
209659
Salmonella enterica subsp. enterica serovar Typhimurium
5'-fluoro-5'-deoxyuridine + NH3
-
-
-
?
3.5.4.5
5'-fluoro-5'-deoxycytidine + H2O
-
209659
Escherichia coli
5'-fluoro-5'-deoxyuridine + NH3
-
-
-
?
3.5.4.5
5-azacytidine + H2O
-
209659
Salmonella enterica subsp. enterica serovar Typhimurium
5-azauridine + NH3
-
-
-
?
3.5.4.5
5-azacytidine + H2O
-
209659
Escherichia coli
5-azauridine + NH3
-
-
-
?
3.5.4.5
5-azacytidine + H2O
-
209659
Homo sapiens
5-azauridine + NH3
-
-
-
?
3.5.4.5
cytidine + H2O
-
209659
Salmonella enterica subsp. enterica serovar Typhimurium
uridine + NH3
-
-
-
?
3.5.4.5
cytidine + H2O
-
209659
Mus musculus
uridine + NH3
-
-
-
?
3.5.4.5
cytidine + H2O
-
209659
Escherichia coli
uridine + NH3
-
-
-
?
3.5.4.5
cytidine + H2O
-
209659
Homo sapiens
uridine + NH3
-
-
-
?
3.5.4.5
cytidine + H2O
-
209659
Saccharomyces cerevisiae
uridine + NH3
-
-
-
?
3.5.4.5
cytidine + H2O
-
209659
Ovis aries
uridine + NH3
-
-
-
?
3.5.4.5
cytidine + H2O
-
209659
Zea mays
uridine + NH3
-
-
-
?
3.5.4.5
cytidine + H2O
-
209659
Mus musculus BALB/c
uridine + NH3
-
-
-
?
3.5.4.5
cytosine arabinoside + H2O
-
209659
Salmonella enterica subsp. enterica serovar Typhimurium
uridine arabinoside + NH3
-
-
-
?
3.5.4.5
cytosine arabinoside + H2O
-
209659
Mus musculus
uridine arabinoside + NH3
-
-
-
?
3.5.4.5
cytosine arabinoside + H2O
-
209659
Escherichia coli
uridine arabinoside + NH3
-
-
-
?
3.5.4.5
cytosine arabinoside + H2O
-
209659
Homo sapiens
uridine arabinoside + NH3
-
-
-
?
3.5.4.5
cytosine arabinoside + H2O
-
209659
Mus musculus BALB/c
uridine arabinoside + NH3
-
-
-
?
3.5.4.5
deoxycytidine + H2O
-
209659
Salmonella enterica subsp. enterica serovar Typhimurium
deoxyuridine + NH3
-
-
-
?
3.5.4.5
deoxycytidine + H2O
-
209659
Mus musculus
deoxyuridine + NH3
-
-
-
?
3.5.4.5
deoxycytidine + H2O
-
209659
Escherichia coli
deoxyuridine + NH3
-
-
-
?
3.5.4.5
deoxycytidine + H2O
-
209659
Homo sapiens
deoxyuridine + NH3
-
-
-
?
3.5.4.5
deoxycytidine + H2O
-
209659
Mus musculus BALB/c
deoxyuridine + NH3
-
-
-
?
3.5.4.5
additional information
cytosine and cytosine nucleotides are no substrates
209659
Salmonella enterica subsp. enterica serovar Typhimurium
?
-
-
-
-
3.5.4.5
additional information
cytosine and cytosine nucleotides are no substrates
209659
Escherichia coli
?
-
-
-
-