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Literature summary extracted from
- Human adenosine deaminase, Distributions and properties (1976), J. Biol. Chem., 251, 5448-5456.
General Stability
| EC Number | General Stability | Organism |
|---|---|---|
| 3.5.4.4 | conversion of smaller enzyme to intermediate and larger enzyme possible | Homo sapiens |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.5.4.4 | cytoplasm | - |
Homo sapiens | 5737 | - |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.5.4.4 | 36000 | - |
gel filtration, type small | Homo sapiens |
| 3.5.4.4 | 114000 | - |
gel filtration, type intermediate | Homo sapiens |
| 3.5.4.4 | 298000 | - |
gel filtration, type large | Homo sapiens |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.5.4.4 | Homo sapiens | - |
normal B-cells and T-cell lines MOLT-4 | - |
| 3.5.4.4 | Homo sapiens | - |
type small, intermediate and large | - |
| 3.5.4.4 | Homo sapiens | - |
RPMI-8402 | - |
| 3.5.4.4 | Homo sapiens | - |
CCRF-CEM | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.5.4.4 | - |
Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.5.4.4 | adrenal gland | - |
Homo sapiens | - |
| 3.5.4.4 | cardiac muscle | - |
Homo sapiens | - |
| 3.5.4.4 | cerebellum | - |
Homo sapiens | - |
| 3.5.4.4 | duodenum | - |
Homo sapiens | - |
| 3.5.4.4 | jejunum | - |
Homo sapiens | - |
| 3.5.4.4 | kidney | - |
Homo sapiens | - |
| 3.5.4.4 | liver | - |
Homo sapiens | - |
| 3.5.4.4 | lung | - |
Homo sapiens | - |
| 3.5.4.4 | lymph node | - |
Homo sapiens | - |
| 3.5.4.4 | pancreas | - |
Homo sapiens | - |
| 3.5.4.4 | skeletal muscle | - |
Homo sapiens | - |
| 3.5.4.4 | spinal cord | - |
Homo sapiens | - |
| 3.5.4.4 | spleen | - |
Homo sapiens | - |
| 3.5.4.4 | stomach | - |
Homo sapiens | - |
| 3.5.4.4 | telencephalon | - |
Homo sapiens | - |
| 3.5.4.4 | testis | - |
Homo sapiens | - |
| 3.5.4.4 | thyroid gland | - |
Homo sapiens | - |
| 3.5.4.4 | vermiform appendix | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.5.4.4 | 0.004 | - |
thyroid | Homo sapiens |
| 3.5.4.4 | 0.006 | - |
kidney | Homo sapiens |
| 3.5.4.4 | 0.007 | - |
lung | Homo sapiens |
| 3.5.4.4 | 0.008 | - |
skeletal muscle | Homo sapiens |
| 3.5.4.4 | 0.009 | - |
liver, cerebellum, spinal cord | Homo sapiens |
| 3.5.4.4 | 0.011 | - |
cardiac muscle | Homo sapiens |
| 3.5.4.4 | 0.013 | - |
testis | Homo sapiens |
| 3.5.4.4 | 0.02 | - |
appendix | Homo sapiens |
| 3.5.4.4 | 0.021 | - |
adrenal gland | Homo sapiens |
| 3.5.4.4 | 0.023 | - |
lymph node | Homo sapiens |
| 3.5.4.4 | 0.027 | - |
pancreas, cerebrum | Homo sapiens |
| 3.5.4.4 | 0.063 | - |
jejunum | Homo sapiens |
| 3.5.4.4 | 0.089 | - |
stomach | Homo sapiens |
| 3.5.4.4 | 0.127 | - |
duodenum | Homo sapiens |
| 3.5.4.4 | 0.128 | - |
spleen | Homo sapiens |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.5.4.4 | adenosine + H2O | - |
Homo sapiens | inosine + NH3 | - |
ir |  |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.5.4.4 | 5.5 | - |
type intermediate | Homo sapiens |
| 3.5.4.4 | 7 | 7.4 | type small and large | Homo sapiens |
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