EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.5.4.3 | 5-aminoimidazole-4-carboxamide | AICA, competitive inhibition | Homo sapiens | |
3.5.4.3 | 5-aminoimidazole-4-carboxamide | AICA, competitive inhibition | Oryctolagus cuniculus | |
3.5.4.3 | 5-aminoimidazole-4-carboxamide | AICA, competitive inhibition | Rattus norvegicus | |
3.5.4.3 | F- | inhibition decreases as pH increases, 50% activity was inhibited at pH 7.5, most of activity lost at pH 6.5 | Homo sapiens | |
3.5.4.3 | F- | inhibition decreases as pH increases, 50% activity was inhibited at pH 7.5, most of activity lost at pH 6.5 | Oryctolagus cuniculus | |
3.5.4.3 | hypoxanthine | - |
Homo sapiens | |
3.5.4.3 | Inosine | - |
Homo sapiens | |
3.5.4.3 | p-hydroxymercuribenzoate | - |
Homo sapiens | |
3.5.4.3 | p-hydroxymercuribenzoate | - |
Oryctolagus cuniculus | |
3.5.4.3 | p-hydroxymercuribenzoate | - |
Rattus norvegicus | |
3.5.4.3 | Rose bengal | photo-oxidation, 0.00025% at acidic pH | Homo sapiens | |
3.5.4.3 | Rose bengal | photo-oxidation, 0.00025% at acidic pH | Oryctolagus cuniculus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.5.4.3 | 0.0074 | - |
guanine | - |
Homo sapiens |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.5.4.3 | 55000 | - |
SDS-PAGE | Homo sapiens |
3.5.4.3 | 55000 | - |
liver, single polypeptide chain, gel filtration | Rattus norvegicus |
3.5.4.3 | 55000 | - |
liver, single polypeptide chain, gel filtration | Oryctolagus cuniculus |
3.5.4.3 | 55000 | - |
2 * 55000, can be converted into monomeric form by addition of sulfhydryl groups | Sus sp. |
3.5.4.3 | 110000 | - |
liver, gel filtration | Homo sapiens |
3.5.4.3 | 110000 | - |
liver, gel filtration | Oryctolagus cuniculus |
3.5.4.3 | 110000 | - |
lung | Rattus norvegicus |
3.5.4.3 | 110000 | - |
brain, gel filtration | Sus sp. |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.5.4.3 | guanine + H2O | Homo sapiens | - |
xanthine + NH3 | - |
? | |
3.5.4.3 | guanine + H2O | Rattus norvegicus | - |
xanthine + NH3 | - |
? | |
3.5.4.3 | guanine + H2O | Oryctolagus cuniculus | - |
xanthine + NH3 | - |
? | |
3.5.4.3 | guanine + H2O | Sus sp. | - |
xanthine + NH3 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.5.4.3 | Homo sapiens | - |
human | - |
3.5.4.3 | Oryctolagus cuniculus | - |
rabbit | - |
3.5.4.3 | Rattus norvegicus | - |
rat | - |
3.5.4.3 | Sus sp. | - |
pig | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.5.4.3 | - |
Homo sapiens |
3.5.4.3 | - |
Rattus norvegicus |
3.5.4.3 | - |
Oryctolagus cuniculus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.5.4.3 | brain | - |
Homo sapiens | - |
3.5.4.3 | brain | - |
Rattus norvegicus | - |
3.5.4.3 | brain | - |
Oryctolagus cuniculus | - |
3.5.4.3 | brain | - |
Sus sp. | - |
3.5.4.3 | liver | - |
Homo sapiens | - |
3.5.4.3 | liver | - |
Rattus norvegicus | - |
3.5.4.3 | liver | - |
Oryctolagus cuniculus | - |
3.5.4.3 | lung | - |
Homo sapiens | - |
3.5.4.3 | lung | - |
Rattus norvegicus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
3.5.4.3 | 22.1 | - |
- |
Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.5.4.3 | guanine + H2O | - |
Homo sapiens | xanthine + NH3 | - |
? | |
3.5.4.3 | guanine + H2O | - |
Rattus norvegicus | xanthine + NH3 | - |
? | |
3.5.4.3 | guanine + H2O | - |
Oryctolagus cuniculus | xanthine + NH3 | - |
? | |
3.5.4.3 | guanine + H2O | - |
Sus sp. | xanthine + NH3 | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
3.5.4.3 | dimer | - |
Rattus norvegicus |
3.5.4.3 | dimer | 2 * 55000, can be converted into monomeric form by addition of sulfhydryl groups | Homo sapiens |
3.5.4.3 | dimer | 2 * 55000, can be converted into monomeric form by addition of sulfhydryl groups | Oryctolagus cuniculus |
3.5.4.3 | dimer | 2 * 55000, can be converted into monomeric form by addition of sulfhydryl groups | Sus sp. |
3.5.4.3 | monomer | - |
Oryctolagus cuniculus |
3.5.4.3 | monomer | liver enzyme | Rattus norvegicus |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.5.4.3 | GAH | - |
Homo sapiens |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.5.4.3 | 7.5 | 9.5 | - |
Homo sapiens |
3.5.4.3 | 7.5 | 9.5 | - |
Rattus norvegicus |
3.5.4.3 | 7.5 | 9.5 | - |
Oryctolagus cuniculus |
3.5.4.3 | 9 | - |
- |
Homo sapiens |
3.5.4.3 | 9 | - |
- |
Sus sp. |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
3.5.4.3 | 5 | 10.5 | - |
Homo sapiens |