Literature summary extracted from

Schoedon, G.; Redweik, U.; Frank, G.; Cotton, R.G.H.; Blau, N.
Allosteric characteristics of GTP cyclohydrolase I from Escherichia coli (1992), Eur. J. Biochem., 210, 561-568.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.5.4.16	L-erythro-5,6,7,8-tetrahydrobiopterin	UTP reduces inhibition	Escherichia coli

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
3.5.4.16	Mg2+	activates	Escherichia coli

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.5.4.16	Escherichia coli	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
3.5.4.16	-	Escherichia coli

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.5.4.16	GTP + H2O	-	Escherichia coli	formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate	-	?

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Release 2023.1 (January 2023)