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Literature summary extracted from

  • Kohashi, M.; Itadani, T.; Iwai, K.
    Purification and characterization of guanosine triphosphate cyclohydrolase from Serratia indica (1980), Agric. Biol. Chem., 44, 271-278.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.4.16 Cd2+
-
 Serratia indica
3.5.4.16 Cu2+
-
 Serratia indica
3.5.4.16 Hg2+
-
 Serratia indica

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.5.4.16 additional information
-
 additional information
-
 Serratia indica

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.5.4.16 K+ activates Serratia indica
3.5.4.16 Li+ activates Serratia indica
3.5.4.16 Na+ activates Serratia indica

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.5.4.16 25000
-
 8 * 25000, SDS-PAGE Serratia indica
3.5.4.16 200000
-
 gel filtration, D-I, D-II Serratia indica

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.4.16 GTP + H2O Serratia indica first step in pathway of pterins formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.5.4.16 Serratia indica
-
 multiple forms, D-I, D-II
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.5.4.16
-
 Serratia indica

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.5.4.16 67
-
-
 Serratia indica

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.4.16 GTP + H2O
-
 Serratia indica formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate
-
 ?
3.5.4.16 GTP + H2O first step in pathway of pterins Serratia indica formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.5.4.16 octamer 8 * 25000, SDS-PAGE Serratia indica