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Literature summary extracted from
- Arginine deiminase inhibits proliferation of human leukemia cells more potently than asparaginase by inducing cell cycle arrest and apoptosis (2000), Leukemia, 14, 826-829.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 3.5.3.6 | medicine | possibility of a future use of arginine deiminase for the therapy of leukemia. The enzyme is 100fold more potent in inhibiting the proliferation of cultured human lymphatic leukemia cell lines while it appears to be less effective in leukemia cells of myeloid origin | Mycoplasmopsis arginini |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.5.3.6 | Mycoplasmopsis arginini | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.5.3.6 | - |
Mycoplasmopsis arginini |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.5.3.6 | L-Arg + H2O | - |
Mycoplasmopsis arginini | L-citrulline + NH3 | - |
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Release 2023.1 (January 2023)
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