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Literature summary extracted from

  • Jacob, E.; Henco, K.; Marcinowski, S.; Schenk, G.
    Verfahren zur Herstellung von mesophilen Mikroorganismen, die eine bei h๖herer Temperatur aktive D-Hydantoinase enthalten (1987), (BASF A. -6) Ger. Offen. DE3535987 A1, (Cl. C12N15/00), , 1-18.
No PubMed abstract available

Application

EC Number Application Comment Organism
3.5.2.2 medicine D-amino acids for preparation of beta-lactam antibiotics like semisynthetic penicillins and cephalosporins such as ampicillin, amoxicillin and cefadroxyl, peptide hormones and pesticides Thermus sp.

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.5.2.2 D-hydantoinase genes cloned and sequenced, Escherichia coli transformed with cosmid vectors, D-hydantoinase expressed and identified Thermus sp.
3.5.2.2 expressed in Escherichia coli BL21 Thermus sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.2.2 hydantoin + H2O Thermus sp.
-
 N-carbamoyl glycine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.5.2.2 Thermus sp.
-
 thermophilic bacterial strains, CBS 303.80 and CBS363.80, asporogenic gram-negative
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.2.2 5,6-dihydrouracil + H2O
-
 Thermus sp. 3-ureidopropionate
-
 ?
3.5.2.2 hydantoin + H2O
-
 Thermus sp. N-carbamoyl glycine
-
 ?