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Literature summary extracted from

  • Morisseau, C.; Beetham, J.K.; Pinot, F.; Debernard, S.; Newman, J.W.; Hammock, B.D.
    Cress and potato soluble epoxide hydrolases: purification, biochemical characterization, and comparison to mammalian enzymes (2000), Arch. Biochem. Biophys., 378, 321-332.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.3.2.10 synthesis potential as biocatalyst for the preparation of enantiopure epoxides Solanum tuberosum
3.3.2.10 synthesis potential as biocatalyst for the preparation of enantiopure epoxides Arabidopsis thaliana

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.3.2.10 baculovirus expression system Solanum tuberosum
3.3.2.10 baculovirus expression system cress

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.3.2.10 2,3-epoxy-1,3-diphenyl-propan-1-one IC50: 0.023 mM Arabidopsis thaliana
3.3.2.10 2,3-epoxy-1,3-diphenyl-propan-1-one IC50: 0.0029 mM Mus musculus
3.3.2.10 2,3-epoxy-1,3-diphenyl-propan-1-one IC50: 0.0034 mM Solanum tuberosum
3.3.2.10 2,3-epoxy-1-(4-bromophenyl)-3-phenyl-propan-1-one IC50: 0.013 mM Arabidopsis thaliana
3.3.2.10 2,3-epoxy-1-(4-bromophenyl)-3-phenyl-propan-1-one IC50: 0.0006 mM Mus musculus
3.3.2.10 2,3-epoxy-1-(4-bromophenyl)-3-phenyl-propan-1-one IC50: 0.00089 mM Solanum tuberosum
3.3.2.10 2,3-epoxy-1-(4-ethylphenyl)-3-phenyl-propan-1-one IC50: 0.03 mM Arabidopsis thaliana
3.3.2.10 2,3-epoxy-1-(4-ethylphenyl)-3-phenyl-propan-1-one IC50: 0.0017 mM Mus musculus
3.3.2.10 2,3-epoxy-1-(4-ethylphenyl)-3-phenyl-propan-1-one IC50: 0.0014 mM Solanum tuberosum
3.3.2.10 2,3-epoxy-1-(4-fluorophenyl)-3-phenyl-propan-1-one IC50: 0.022 mM Arabidopsis thaliana
3.3.2.10 2,3-epoxy-1-(4-fluorophenyl)-3-phenyl-propan-1-one IC50: 0.0018 mM Mus musculus
3.3.2.10 2,3-epoxy-1-(4-fluorophenyl)-3-phenyl-propan-1-one IC50: 0.0012 mM Solanum tuberosum
3.3.2.10 2,3-epoxy-1-(4-methoxyphenyl)-3-phenyl-propan-1-one IC50: 0.0054 mM Arabidopsis thaliana
3.3.2.10 2,3-epoxy-1-(4-methoxyphenyl)-3-phenyl-propan-1-one IC50: 0.00032 mM Mus musculus
3.3.2.10 2,3-epoxy-1-(4-methoxyphenyl)-3-phenyl-propan-1-one IC50: 0.00021 mM Solanum tuberosum
3.3.2.10 2,3-epoxy-1-(4-nitroxyphenyl)-3-phenyl-propan-1-one IC50: 0.016 mM Arabidopsis thaliana
3.3.2.10 2,3-epoxy-1-(4-nitroxyphenyl)-3-phenyl-propan-1-one IC50: 0.0015 mM Mus musculus
3.3.2.10 2,3-epoxy-1-(4-nitroxyphenyl)-3-phenyl-propan-1-one IC50: 0.019 mM Solanum tuberosum
3.3.2.10 2,3-epoxy-1-(4-phenylphenyl)-3-phenyl-propan-1-one IC50: 0.00137 mM Mus musculus
3.3.2.10 2,3-epoxy-1-(4-phenylphenyl)-3-phenyl-propan-1-one IC50: 0.0025 mM Solanum tuberosum
3.3.2.10 2,3-epoxy-3-(4-bromophenyl)-1-phenyl-propan-1-one IC50: 0.0022 mM Arabidopsis thaliana
3.3.2.10 2,3-epoxy-3-(4-bromophenyl)-1-phenyl-propan-1-one IC50: 0.0007 mM Mus musculus
3.3.2.10 2,3-epoxy-3-(4-bromophenyl)-1-phenyl-propan-1-one IC50: 0.00012 mM Solanum tuberosum
3.3.2.10 2,3-epoxy-3-(4-ethylphenyl)-1-phenyl-propan-1-one IC50: 0.0056 mM Arabidopsis thaliana
3.3.2.10 2,3-epoxy-3-(4-ethylphenyl)-1-phenyl-propan-1-one IC50: 0.0019 mM Mus musculus
3.3.2.10 2,3-epoxy-3-(4-ethylphenyl)-1-phenyl-propan-1-one IC50: 0.00016 mM Solanum tuberosum
3.3.2.10 2,3-epoxy-3-(4-fluorophenyl)-1-phenyl-propan-1-one IC50: 0.0047 mM Arabidopsis thaliana
3.3.2.10 2,3-epoxy-3-(4-fluorophenyl)-1-phenyl-propan-1-one IC50: 0.0013 mM Mus musculus
3.3.2.10 2,3-epoxy-3-(4-fluorophenyl)-1-phenyl-propan-1-one IC50: 0.00048 mM Solanum tuberosum
3.3.2.10 2,3-epoxy-3-(4-methoxyphenyl)-1-phenyl-propan-1-one IC50: 0.0028 mM Arabidopsis thaliana
3.3.2.10 2,3-epoxy-3-(4-methoxyphenyl)-1-phenyl-propan-1-one IC50: 0.0002 mM Mus musculus
3.3.2.10 2,3-epoxy-3-(4-methoxyphenyl)-1-phenyl-propan-1-one IC50: 0.00019 mM Solanum tuberosum
3.3.2.10 2,3-epoxy-3-(4-n-butylphenyl)-1-phenyl-propan-1-one IC50: 0.0017 mM Arabidopsis thaliana
3.3.2.10 2,3-epoxy-3-(4-n-butylphenyl)-1-phenyl-propan-1-one IC50: 0.00015 mM Mus musculus
3.3.2.10 2,3-epoxy-3-(4-nitrophenyl)-1-phenyl-propan-1-one IC50: 0.011 mM Arabidopsis thaliana
3.3.2.10 2,3-epoxy-3-(4-nitrophenyl)-1-phenyl-propan-1-one IC50: 0.00018 mM Mus musculus
3.3.2.10 2,3-epoxy-3-(4-nitrophenyl)-1-phenyl-propan-1-one IC50: 0.00038 mM Solanum tuberosum
3.3.2.10 2,3-epoxy-3-(4-phenylphenyl)-1-phenyl-propan-1-one IC50: 0.00014 mM Mus musculus
3.3.2.10 4-bromo-4'-methoxychalcone IC50: 0.0048 mM Arabidopsis thaliana
3.3.2.10 4-bromo-4'-methoxychalcone IC50: 0.00027 mM Mus musculus
3.3.2.10 4-bromo-4'-methoxychalcone IC50: 0.00021 mM Solanum tuberosum
3.3.2.10 Chalcone oxide
-
 cress
3.3.2.10 Chalcone oxide
-
 Mus musculus
3.3.2.10 Chalcone oxide
-
 Solanum tuberosum

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.3.2.10 additional information
-
 additional information
-
 Rattus norvegicus
3.3.2.10 additional information
-
 additional information
-
 Solanum tuberosum
3.3.2.10 additional information
-
 additional information
-
 cress
3.3.2.10 0.0043
-
 2,3-epoxy-1,3-diphenyl-propane 30°C Mus musculus
3.3.2.10 0.0062
-
 2,3-epoxy-1,3-diphenyl-propane 30°C Homo sapiens
3.3.2.10 0.0069
-
 2,3-epoxy-1,3-diphenyl-propane 30°C Rattus norvegicus
3.3.2.10 0.007
-
 2,3-epoxy-1,3-diphenyl-propane 30°C Arabidopsis thaliana
3.3.2.10 0.0083
-
 2,3-epoxy-1,3-diphenyl-propane 30°C Solanum tuberosum

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.3.2.10 soluble
-
 Solanum tuberosum
-
-
3.3.2.10 soluble
-
 Arabidopsis thaliana
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.3.2.10 36000
-
 1 * 36000, SDS-PAGE Arabidopsis thaliana
3.3.2.10 36000
-
 1 * 36000, SDS-PAGE cress
3.3.2.10 39000
-
 1 * 39000, SDS-PAGE Solanum tuberosum
3.3.2.10 40000
-
 gel filtration Solanum tuberosum
3.3.2.10 40000
-
 gel filtration cress
3.3.2.10 40000
-
 about, gel filtration Solanum tuberosum
3.3.2.10 40000
-
 about, gel filtration Arabidopsis thaliana
3.3.2.10 60000
-
 2 * 60000, SDS-PAGE Mus musculus
3.3.2.10 60000
-
 2 * 60000, SDS-PAGE Homo sapiens
3.3.2.10 60000
-
 2 * 60000, SDS-PAGE Rattus norvegicus
3.3.2.10 130000
-
 about, gel filtration Mus musculus
3.3.2.10 130000
-
 about, gel filtration Homo sapiens
3.3.2.10 130000
-
 about, gel filtration Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.3.2.10 Arabidopsis thaliana
-
 Thale cress
-
3.3.2.10 cress
-
-
-
3.3.2.10 Homo sapiens
-
-
-
3.3.2.10 Mus musculus
-
-
-
3.3.2.10 Rattus norvegicus
-
-
-
3.3.2.10 Solanum tuberosum
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.3.2.10
-
 Solanum tuberosum
3.3.2.10
-
 Arabidopsis thaliana
3.3.2.10
-
 cress

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.3.2.10 2.67
-
-
 Solanum tuberosum
3.3.2.10 3.9
-
-
 Arabidopsis thaliana
3.3.2.10 3.91
-
-
 cress

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.3.2.10 1,3-trans-diphenylpropene oxide + H2O little to no selectivity for cis-isomer or trans-isomer Arabidopsis thaliana 1,3-diphenylpropane-1,2-diol
-
 ?
3.3.2.10 2,3-epoxy-1,3-diphenyl-propane + H2O
-
 Mus musculus ?
-
 ?
3.3.2.10 2,3-epoxy-1,3-diphenyl-propane + H2O
-
 Homo sapiens ?
-
 ?
3.3.2.10 2,3-epoxy-1,3-diphenyl-propane + H2O
-
 Rattus norvegicus ?
-
 ?
3.3.2.10 2,3-epoxy-1,3-diphenyl-propane + H2O
-
 Solanum tuberosum ?
-
 ?
3.3.2.10 2,3-epoxy-1,3-diphenyl-propane + H2O
-
 Arabidopsis thaliana ?
-
 ?
3.3.2.10 4-nitrophenyl (2R,3R)-2,3-epoxy-3-phenylpropyl carbonate + H2O 14.6% of the activity with 2,3-epoxy-1,3-diphenyl-propane, no activity with the 2S,3S-enantiomer Homo sapiens ?
-
 ?
3.3.2.10 4-nitrophenyl (2R,3R)-2,3-epoxy-3-phenylpropyl carbonate + H2O 5.1% of the activity with 2,3-epoxy-1,3-diphenyl-propane, no activity with the 2S,3S-enantiomer Rattus norvegicus ?
-
 ?
3.3.2.10 4-nitrophenyl [(2R,3R)-3-phenyloxiran-2-yl]methyl carbonate + H2O 15.2% of the activity with 2,3-epoxy-1,3-diphenyl-propane Arabidopsis thaliana ?
-
 ?
3.3.2.10 4-nitrophenyl [(2S,3S)-3-phenyloxiran-2-yl]methyl carbonate + H2O 38% of the activity with 2,3-epoxy-1,3-diphenyl-propane Arabidopsis thaliana ?
-
 ?
3.3.2.10 cis-1,3-diphenylpropene oxide + H2O 2.1% of the activity with 2,3-epoxy-1,3-diphenyl-propane Rattus norvegicus 1,3-diphenylpropane-1,2-diol
-
 ?
3.3.2.10 cis-1,3-diphenylpropene oxide + H2O little to no selectivity for cis-isomer or trans-isomer, 44% of the activity with 2,3-epoxy-1,3-diphenyl-propane Solanum tuberosum 1,3-diphenylpropane-1,2-diol
-
 ?
3.3.2.10 cis-1,3-diphenylpropene oxide + H2O little to no selectivity for cis-isomer or trans-isomer, 99% of the activity with 2,3-epoxy-1,3-diphenyl-propane Arabidopsis thaliana 1,3-diphenylpropane-1,2-diol
-
 ?
3.3.2.10 cis-1,3-diphenylpropene oxide + H2O 18.1% of the activity with 2,3-epoxy-1,3-diphenyl-propane Homo sapiens ?
-
 ?
3.3.2.10 cis-1,3-diphenylpropene oxide + H2O 3.0% of the activity with 2,3-epoxy-1,3-diphenyl-propane Mus musculus ?
-
 ?
3.3.2.10 cis-9,10-epoxy-12-octadecenoate methyl ester + H2O 12% of the activity with 2,3-epoxy-1,3-diphenyl-propane Solanum tuberosum 9,10-dihydroxystearic acid methyl ester
-
 ?
3.3.2.10 cis-9,10-epoxy-12-octadecenoate methyl ester + H2O 3.5% of the activity with 2,3-epoxy-1,3-diphenyl-propane Rattus norvegicus 9,10-dihydroxystearic acid methyl ester
-
 ?
3.3.2.10 cis-9,10-epoxy-12-octadecenoate methyl ester + H2O 59% of the activity with 2,3-epoxy-1,3-diphenyl-propane Arabidopsis thaliana 9,10-dihydroxystearic acid methyl ester
-
 ?
3.3.2.10 cis-9,10-epoxy-12-octadecenoate methyl ester + H2O 6.5% of the activity with 2,3-epoxy-1,3-diphenyl-propane Mus musculus 9,10-dihydroxystearic acid methyl ester
-
 ?
3.3.2.10 cis-9,10-epoxy-12-octadecenoate methyl ester + H2O 5.2% of the activity with 2,3-epoxy-1,3-diphenyl-propane Homo sapiens ?
-
 ?
3.3.2.10 cis-9,10-epoxystearic acid + H2O 13.4% of the activity with 2,3-epoxy-1,3-diphenyl-propane Solanum tuberosum 9,10-dihydroxystearic acid
-
 ?
3.3.2.10 cis-9,10-epoxystearic acid + H2O 30% of the activity with 2,3-epoxy-1,3-diphenyl-propane Arabidopsis thaliana 9,10-dihydroxystearic acid
-
 ?
3.3.2.10 cis-9,10-epoxystearic acid + H2O 4.1% of the activity with 2,3-epoxy-1,3-diphenyl-propane Rattus norvegicus 9,10-dihydroxystearic acid
-
 ?
3.3.2.10 cis-9,10-epoxystearic acid + H2O 6.7% of the activity with 2,3-epoxy-1,3-diphenyl-propane Mus musculus 9,10-dihydroxystearic acid
-
 ?
3.3.2.10 cis-9,10-epoxystearic acid + H2O 7.9% of the activity with 2,3-epoxy-1,3-diphenyl-propane Homo sapiens ?
-
 ?
3.3.2.10 cis-stilbene oxide + H2O
-
 Mus musculus ?
-
 ?
3.3.2.10 cis-stilbene oxide + H2O
-
 Homo sapiens ?
-
 ?
3.3.2.10 cis-stilbene oxide + H2O
-
 Rattus norvegicus ?
-
 ?
3.3.2.10 cis-stilbene oxide + H2O greater selectivity for trans-stilbene oxide versus cis-stilbene oxide Solanum tuberosum ?
-
 ?
3.3.2.10 cis-stilbene oxide + H2O greater selectivity for trans-stilbene oxide versus cis-stilbene oxide cress ?
-
 ?
3.3.2.10 cis-stilbene oxide + H2O 0.4% of the activity with 2,3-epoxy-1,3-diphenyl-propane Mus musculus 1,2-diphenylethane-1,2-diol
-
 ?
3.3.2.10 cis-stilbene oxide + H2O far greater selectivity for trans-stilbene oxide versus cis-stilbene oxide. 0.06% of the activity with 2,3-epoxy-1,3-diphenyl-propane Solanum tuberosum 1,2-diphenylethane-1,2-diol
-
 ?
3.3.2.10 cis-stilbene oxide + H2O far greater selectivity for trans-stilbene oxide versus cis-stilbene oxide. 0.2% of the activity with 2,3-epoxy-1,3-diphenyl-propane Arabidopsis thaliana 1,2-diphenylethane-1,2-diol
-
 ?
3.3.2.10 juvenile hormone III + H2O 11.9% of the activity with 2,3-epoxy-1,3-diphenyl-propane Arabidopsis thaliana ?
-
 ?
3.3.2.10 juvenile hormone III + H2O 3.5% of the activity with 2,3-epoxy-1,3-diphenyl-propane Rattus norvegicus ?
-
 ?
3.3.2.10 juvenile hormone III + H2O 6.3% of the activity with 2,3-epoxy-1,3-diphenyl-propane Mus musculus ?
-
 ?
3.3.2.10 juvenile hormone III + H2O 6.3% of the activity with 2,3-epoxy-1,3-diphenyl-propane Homo sapiens ?
-
 ?
3.3.2.10 juvenile hormone III + H2O 7.1% of the activity with 2,3-epoxy-1,3-diphenyl-propane Solanum tuberosum ?
-
 ?
3.3.2.10 trans-1,3-diphenylpropene oxide + H2O
-
 Solanum tuberosum ?
-
 ?
3.3.2.10 trans-1,3-diphenylpropene oxide + H2O
-
 cress ?
-
 ?
3.3.2.10 trans-1,3-diphenylpropene oxide + H2O little to no selectivity for cis-isomer or trans-isomer Solanum tuberosum 1,3-diphenylpropane-1,2-diol
-
 ?
3.3.2.10 trans-stilbene oxide + H2O
-
 Mus musculus ?
-
 ?
3.3.2.10 trans-stilbene oxide + H2O
-
 Homo sapiens ?
-
 ?
3.3.2.10 trans-stilbene oxide + H2O
-
 Rattus norvegicus ?
-
 ?
3.3.2.10 trans-stilbene oxide + H2O greater selectivity for trans-stilbene oxide versus cis-stilbene oxide Solanum tuberosum ?
-
 ?
3.3.2.10 trans-stilbene oxide + H2O greater selectivity for trans-stilbene oxide versus cis-stilbene oxide cress ?
-
 ?
3.3.2.10 trans-stilbene oxide + H2O highly selective for the trans-enantiomer. 1.2% of the activity with 2,3-epoxy-1,3-diphenyl-propane Homo sapiens ?
-
 ?
3.3.2.10 trans-stilbene oxide + H2O 2.8% of the activity with 2,3-epoxy-1,3-diphenyl-propane Mus musculus 1,2-diphenylethane-1,2-diol
-
 ?
3.3.2.10 trans-stilbene oxide + H2O far greater selectivity for trans-stilbene oxide versus cis-stilbene oxide. 5.6% of the activity with 2,3-epoxy-1,3-diphenyl-propane Solanum tuberosum 1,2-diphenylethane-1,2-diol
-
 ?
3.3.2.10 trans-stilbene oxide + H2O far greater selectivity for trans-stilbene oxide versus cis-stilbene oxide. 84% of the activity with 2,3-epoxy-1,3-diphenyl-propane Arabidopsis thaliana 1,2-diphenylethane-1,2-diol
-
 ?
3.3.2.10 trans-stilbene oxide + H2O highly selective for the trans-enantiomer. 1% of the activity with 2,3-epoxy-1,3-diphenyl-propane Rattus norvegicus 1,2-diphenylethane-1,2-diol
-
 ?

Subunits

EC Number Subunits Comment Organism
3.3.2.10 dimer 2 * 60000, SDS-PAGE Mus musculus
3.3.2.10 dimer 2 * 60000, SDS-PAGE Homo sapiens
3.3.2.10 dimer 2 * 60000, SDS-PAGE Rattus norvegicus
3.3.2.10 monomer
-
 Mus musculus
3.3.2.10 monomer
-
 Homo sapiens
3.3.2.10 monomer 1 * 39000, SDS-PAGE Solanum tuberosum
3.3.2.10 monomer 1 * 36000, SDS-PAGE Arabidopsis thaliana
3.3.2.10 monomer 1 * 36000, SDS-PAGE cress

Synonyms

EC Number Synonyms Comment Organism
3.3.2.10 PsEH
-
 Solanum tuberosum

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.3.2.10 30
-
 t1/2 is 17.4 h Mus musculus
3.3.2.10 30
-
 t1/2: 20.3 h Rattus norvegicus
3.3.2.10 30
-
 t1/2: 8.1 h Homo sapiens
3.3.2.10 37
-
-
 Solanum tuberosum
3.3.2.10 37
-
 t1/2: more than 24 h cress
3.3.2.10 37
-
 t1/2: 2.0 h Rattus norvegicus
3.3.2.10 37
-
 t1/2: 18 h Mus musculus
3.3.2.10 37
-
 t1/2: 1.3 h Homo sapiens
3.3.2.10 37
-
 t1/2: 2 h Rattus norvegicus
3.3.2.10 37
-
 t1/2 is 1.8 h Mus musculus
3.3.2.10 45
-
 t1/2 is 10.2 h Arabidopsis thaliana
3.3.2.10 51
-
 t1/2: more than 24 h Solanum tuberosum
3.3.2.10 51
-
 t1/2: 6.4 h cress
3.3.2.10 51
-
 t1/2 is 6.4 h Arabidopsis thaliana
3.3.2.10 55
-
 t1/2: 0.93 h cress
3.3.2.10 55
-
 t1/2: 4.7 h Solanum tuberosum
3.3.2.10 55
-
 t1/2 is 0.93 h Arabidopsis thaliana
3.3.2.10 55
-
 t1/2 is 4.7 h Solanum tuberosum
3.3.2.10 59
-
 t1/2: 0.38 h cress
3.3.2.10 59
-
 t1/2: 0.87 h Solanum tuberosum
3.3.2.10 59
-
 t1/2 is 0.38 h Arabidopsis thaliana
3.3.2.10 59
-
 t1/2 is 0.87 h Solanum tuberosum

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.3.2.10 additional information
-
 additional information
-
 Solanum tuberosum
3.3.2.10 additional information
-
 additional information
-
 cress
3.3.2.10 1.64
-
 2,3-epoxy-1,3-diphenyl-propane 30°C Arabidopsis thaliana
3.3.2.10 4.3
-
 2,3-epoxy-1,3-diphenyl-propane 30°C Homo sapiens
3.3.2.10 4.76
-
 2,3-epoxy-1,3-diphenyl-propane 30°C Solanum tuberosum
3.3.2.10 12
-
 2,3-epoxy-1,3-diphenyl-propane 30°C Rattus norvegicus
3.3.2.10 18
-
 2,3-epoxy-1,3-diphenyl-propane 30°C Mus musculus

pI Value

EC Number Organism Comment pI Value Maximum pI Value
3.3.2.10 Arabidopsis thaliana electrofocusing, pH-gradient 3.0-7.0
-
 4.5
3.3.2.10 Solanum tuberosum electrofocusing, pH-gradient 3.0-7.0
-
 5
3.3.2.10 Mus musculus electrofocusing, pH-gradient 3.0-7.0
-
 5.5
3.3.2.10 Homo sapiens electrofocusing, pH-gradient 3.0-7.0
-
 5.5
3.3.2.10 Rattus norvegicus electrofocusing, pH-gradient 3.0-7.0
-
 5.5

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
3.3.2.10 0.00012
-
 IC50: 0.00012 mM Solanum tuberosum 2,3-epoxy-3-(4-bromophenyl)-1-phenyl-propan-1-one
3.3.2.10 0.00014
-
 IC50: 0.00014 mM Mus musculus 2,3-epoxy-3-(4-phenylphenyl)-1-phenyl-propan-1-one
3.3.2.10 0.00015
-
 IC50: 0.00015 mM Mus musculus 2,3-epoxy-3-(4-n-butylphenyl)-1-phenyl-propan-1-one
3.3.2.10 0.00016
-
 IC50: 0.00016 mM Solanum tuberosum 2,3-epoxy-3-(4-ethylphenyl)-1-phenyl-propan-1-one
3.3.2.10 0.00018
-
 IC50: 0.00018 mM Mus musculus 2,3-epoxy-3-(4-nitrophenyl)-1-phenyl-propan-1-one
3.3.2.10 0.00019
-
 IC50: 0.00019 mM Solanum tuberosum 2,3-epoxy-3-(4-methoxyphenyl)-1-phenyl-propan-1-one
3.3.2.10 0.0002
-
 IC50: 0.0002 mM Mus musculus 2,3-epoxy-3-(4-methoxyphenyl)-1-phenyl-propan-1-one
3.3.2.10 0.00021
-
 IC50: 0.00021 mM Solanum tuberosum 2,3-epoxy-1-(4-methoxyphenyl)-3-phenyl-propan-1-one
3.3.2.10 0.00021
-
 IC50: 0.00021 mM Solanum tuberosum 4-bromo-4'-methoxychalcone
3.3.2.10 0.00027
-
 IC50: 0.00027 mM Mus musculus 4-bromo-4'-methoxychalcone
3.3.2.10 0.00032
-
 IC50: 0.00032 mM Mus musculus 2,3-epoxy-1-(4-methoxyphenyl)-3-phenyl-propan-1-one
3.3.2.10 0.00038
-
 IC50: 0.00038 mM Solanum tuberosum 2,3-epoxy-3-(4-nitrophenyl)-1-phenyl-propan-1-one
3.3.2.10 0.00048
-
 IC50: 0.00048 mM Solanum tuberosum 2,3-epoxy-3-(4-fluorophenyl)-1-phenyl-propan-1-one
3.3.2.10 0.0006
-
 IC50: 0.0006 mM Mus musculus 2,3-epoxy-1-(4-bromophenyl)-3-phenyl-propan-1-one
3.3.2.10 0.0007
-
 IC50: 0.0007 mM Mus musculus 2,3-epoxy-3-(4-bromophenyl)-1-phenyl-propan-1-one
3.3.2.10 0.00089
-
 IC50: 0.00089 mM Solanum tuberosum 2,3-epoxy-1-(4-bromophenyl)-3-phenyl-propan-1-one
3.3.2.10 0.0012
-
 IC50: 0.0012 mM Solanum tuberosum 2,3-epoxy-1-(4-fluorophenyl)-3-phenyl-propan-1-one
3.3.2.10 0.0013
-
 IC50: 0.0013 mM Mus musculus 2,3-epoxy-3-(4-fluorophenyl)-1-phenyl-propan-1-one
3.3.2.10 0.00137
-
 IC50: 0.00137 mM Mus musculus 2,3-epoxy-1-(4-phenylphenyl)-3-phenyl-propan-1-one
3.3.2.10 0.0014
-
 IC50: 0.0014 mM Solanum tuberosum 2,3-epoxy-1-(4-ethylphenyl)-3-phenyl-propan-1-one
3.3.2.10 0.0015
-
 IC50: 0.0015 mM Mus musculus 2,3-epoxy-1-(4-nitroxyphenyl)-3-phenyl-propan-1-one
3.3.2.10 0.0017
-
 IC50: 0.0017 mM Mus musculus 2,3-epoxy-1-(4-ethylphenyl)-3-phenyl-propan-1-one
3.3.2.10 0.0017
-
 IC50: 0.0017 mM Arabidopsis thaliana 2,3-epoxy-3-(4-n-butylphenyl)-1-phenyl-propan-1-one
3.3.2.10 0.0018
-
 IC50: 0.0018 mM Mus musculus 2,3-epoxy-1-(4-fluorophenyl)-3-phenyl-propan-1-one
3.3.2.10 0.0019
-
 IC50: 0.0019 mM Mus musculus 2,3-epoxy-3-(4-ethylphenyl)-1-phenyl-propan-1-one
3.3.2.10 0.0022
-
 IC50: 0.0022 mM Arabidopsis thaliana 2,3-epoxy-3-(4-bromophenyl)-1-phenyl-propan-1-one
3.3.2.10 0.0025
-
 IC50: 0.0025 mM Solanum tuberosum 2,3-epoxy-1-(4-phenylphenyl)-3-phenyl-propan-1-one
3.3.2.10 0.0028
-
 IC50: 0.0028 mM Arabidopsis thaliana 2,3-epoxy-3-(4-methoxyphenyl)-1-phenyl-propan-1-one
3.3.2.10 0.0029
-
 IC50: 0.0029 mM Mus musculus 2,3-epoxy-1,3-diphenyl-propan-1-one
3.3.2.10 0.0034
-
 IC50: 0.0034 mM Solanum tuberosum 2,3-epoxy-1,3-diphenyl-propan-1-one
3.3.2.10 0.0047
-
 IC50: 0.0047 mM Arabidopsis thaliana 2,3-epoxy-3-(4-fluorophenyl)-1-phenyl-propan-1-one
3.3.2.10 0.0048
-
 IC50: 0.0048 mM Arabidopsis thaliana 4-bromo-4'-methoxychalcone
3.3.2.10 0.0054
-
 IC50: 0.0054 mM Arabidopsis thaliana 2,3-epoxy-1-(4-methoxyphenyl)-3-phenyl-propan-1-one
3.3.2.10 0.0056
-
 IC50: 0.0056 mM Arabidopsis thaliana 2,3-epoxy-3-(4-ethylphenyl)-1-phenyl-propan-1-one
3.3.2.10 0.011
-
 IC50: 0.011 mM Arabidopsis thaliana 2,3-epoxy-3-(4-nitrophenyl)-1-phenyl-propan-1-one
3.3.2.10 0.013
-
 IC50: 0.013 mM Arabidopsis thaliana 2,3-epoxy-1-(4-bromophenyl)-3-phenyl-propan-1-one
3.3.2.10 0.016
-
 IC50: 0.016 mM Arabidopsis thaliana 2,3-epoxy-1-(4-nitroxyphenyl)-3-phenyl-propan-1-one
3.3.2.10 0.019
-
 IC50: 0.019 mM Solanum tuberosum 2,3-epoxy-1-(4-nitroxyphenyl)-3-phenyl-propan-1-one
3.3.2.10 0.022
-
 IC50: 0.022 mM Arabidopsis thaliana 2,3-epoxy-1-(4-fluorophenyl)-3-phenyl-propan-1-one
3.3.2.10 0.023
-
 IC50: 0.023 mM Arabidopsis thaliana 2,3-epoxy-1,3-diphenyl-propan-1-one
3.3.2.10 0.03
-
 IC50: 0.03 mM Arabidopsis thaliana 2,3-epoxy-1-(4-ethylphenyl)-3-phenyl-propan-1-one