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Literature summary extracted from
- Purification of poly(ADP-ribose) glycohydrolase detection of its isoforms by a zymogram following one- or two-dimensional electrophoresis (1994), Anal. Biochem., 218, 265-272.
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.2.1.143 | 60000 | - |
x * 60000, poly(ADP-ribose) glycohydrolase G1, G2 and G3, SDS-PAGE | Bos taurus |
| 3.2.1.143 | 74000 | - |
x * 74000, poly(ADP-ribose) glycohydrolase G4, SDS-PAGE | Bos taurus |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.2.1.143 | poly(ADP-ribose)n + H2O | Bos taurus | the enzyme is responsible for the catabolism of poly(ADP-ribose), the enzyme is a crucial determinant of polymer metabolism which is known to be implicated in DNA repair and other cellular processes | ? | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.2.1.143 | Bos taurus | - |
calf | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.2.1.143 | 4 poly(ADP-ribose) glycohydrolase isoforms: G1, G2, G3, G4 | Bos taurus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.2.1.143 | thymus | - |
Bos taurus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.2.1.143 | 69.95 | - |
- |
Bos taurus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.2.1.143 | poly(ADP-ribose)n + H2O | - |
Bos taurus | ADP-ribose | - |
? | |
| 3.2.1.143 | poly(ADP-ribose)n + H2O | the enzyme is responsible for the catabolism of poly(ADP-ribose), the enzyme is a crucial determinant of polymer metabolism which is known to be implicated in DNA repair and other cellular processes | Bos taurus | ? | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.2.1.143 | ? | x * 74000, poly(ADP-ribose) glycohydrolase G4, SDS-PAGE | Bos taurus |
| 3.2.1.143 | ? | x * 60000, poly(ADP-ribose) glycohydrolase G1, G2 and G3, SDS-PAGE | Bos taurus |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.2.1.143 | PARG | - |
Bos taurus |
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