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Literature summary extracted from

  • Rebbe, N.F.; Tong, B.D.; Finley, E.M.; Hickman, S.
    Identification of nucleotide pyrophosphatase/alkaline phosphodiesterase I activity associated with the mouse plasma cell differentiation antigen PC-1 (1991), Proc. Natl. Acad. Sci. USA, 88, 5192-5196.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.4.1 dexamethasone PC-1, nucleotide pyrophosphatase/alkaline phosphodiesterase I Mus musculus

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.4.1 cDNA encoding PC-1 Mus musculus
3.1.4.1 nucleotide pyrophosphatase/alkaline phosphodiesterase I, transformed into Escherichia coli Mus musculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.4.1 EDTA PC-1 Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.4.1 cytoplasmic membrane PC-1 Mus musculus
-
-
3.1.4.1 cytoplasmic membrane PC-1 is a type-II membrane protein Mus musculus
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.4.1 115000
-
 2 * 115000, PC-1, SDS-PAGE Mus musculus
3.1.4.1 220000
-
 PC-1, SDS-PAGE Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.4.1 additional information Mus musculus PC-1, nucleotide pyrophosphatase/alkaline phosphodiesterase I, may have a role in the regulation of N-linked glycosylation, it may regulate the availability of nucleotide sugar precusors at the site of oligosaccharide synthesis ?
-
 ?
3.1.4.1 additional information Mus musculus BALB/c PC-1, nucleotide pyrophosphatase/alkaline phosphodiesterase I, may have a role in the regulation of N-linked glycosylation, it may regulate the availability of nucleotide sugar precusors at the site of oligosaccharide synthesis ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.1 Mus musculus
-
 PC-1
-
3.1.4.1 Mus musculus
-
 BALB/c
-
3.1.4.1 Mus musculus BALB/c
-
 BALB/c
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.1.4.1 glycoprotein PC-1, containing N-linked oligosaccharides Mus musculus

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.4.1 PC-1 Mus musculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.4.1 MOPC 315 cell MOPC 315 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.1 additional information PC-1, nucleotide pyrophosphatase/alkaline phosphodiesterase I, may have a role in the regulation of N-linked glycosylation, it may regulate the availability of nucleotide sugar precusors at the site of oligosaccharide synthesis Mus musculus ?
-
 ?
3.1.4.1 additional information PC-1, nucleotide pyrophosphatase/alkaline phosphodiesterase I, may have a role in the regulation of N-linked glycosylation, it may regulate the availability of nucleotide sugar precusors at the site of oligosaccharide synthesis Mus musculus BALB/c ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.4.1 dimer 2 * 115000, PC-1, SDS-PAGE Mus musculus

Synonyms

EC Number Synonyms Comment Organism
3.1.4.1 nucleotide pyrophosphatase/alkaline phosphodiesterase I EC 3.6.1.9 /EC 3.1.4.1 Mus musculus
3.1.4.1 PC-1 PC-1, plasma-cell differentiation antigen-1, membrane glycoprotein, has 5'-nucleotide phosphodiesterase and nucleotide pyrophosphatase activity Mus musculus