BRENDA - Enzyme Database

Synthesis of an inhibitor of glutamyl-tRNA synthetase

Dorion, C.; Chenvert, R.; Lacoste, L.; Lapointe, J.; Bioorg. Med. Chem. Lett. 3, 2699-2702 (1993)
No PubMed abstract available

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
6.1.1.17
N6-Benzoyl-L-glutamyl AMP
specific for glutamyl-tRNA synthetase, does not inhibit glutaminyl-tRNA synthetase
Escherichia coli
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
6.1.1.17
Escherichia coli
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
6.1.1.17
ATP + L-glutamate + tRNAGlu
-
201
Escherichia coli
AMP + diphosphate + L-glutamyl-tRNAGlu
-
201
Escherichia coli
-
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
6.1.1.17
N6-Benzoyl-L-glutamyl AMP
specific for glutamyl-tRNA synthetase, does not inhibit glutaminyl-tRNA synthetase
Escherichia coli
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
6.1.1.17
ATP + L-glutamate + tRNAGlu
-
201
Escherichia coli
AMP + diphosphate + L-glutamyl-tRNAGlu
-
201
Escherichia coli
-