Literature summary extracted from

Carver, J.A.; Baldwin, G.S.; Keech, D.B.; Bais, R.; Wallace, J.C.
Inactivation of chicken liver pyruvate carboxylase by 1,10-phenanthroline (1988), Biochem. J., 252, 501-507.

General Stability

EC Number	General Stability	Organism
6.4.1.1	does not participate directly in the reaction mechanism, but may play a structural role essential to the integrity of the enzymes tetrameric structure	Gallus gallus

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
6.4.1.1	1,10-phenanthroline	inactivation follows pseudo-first-order kinetics, the rate of inactivation is greater at low enzyme concentrations	Gallus gallus

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
6.4.1.1	Mn2+	does not participate directly in the reaction mechanism, but may play a structural role essential to the integrity of the enzymes tetrameric structure	Gallus gallus

Organism

EC Number	Organism	UniProt	Comment	Textmining
6.4.1.1	Gallus gallus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
6.4.1.1	liver	-	Gallus gallus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
6.4.1.1	ATP + pyruvate + HCO3-	-	Gallus gallus	ADP + phosphate + oxaloacetate	-	?

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Release 2023.1 (January 2023)