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Literature summary extracted from

  • Baricos, W.H.; Cortez-Schwartz, S.; Shah, S.V.
    Renal neuraminidase: characterization in normal rat kidney and measurement in experimentally induced nephrotic syndrome (1986), Biochem. J., 239, 705-710.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.18 alpha-D-N-acetylneuraminic acid
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.2.1.18 0.2
-
 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid glomeruli Rattus norvegicus
3.2.1.18 0.23
-
 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid cortex Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.18 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.18 kidney
-
 Rattus norvegicus
-
3.2.1.18 liver
-
 Rattus norvegicus
-

Storage Stability

EC Number Storage Stability Organism
3.2.1.18 -20°C Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.18 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid + H2O
-
 Rattus norvegicus 4-methylumbelliferone + N-acetylneuraminic acid
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.2.1.18 4.4
-
-
 Rattus norvegicus