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Literature summary extracted from

  • Han, P.F.; Owen, G.S.; Johnson, J.
    Purification and properties of fructose 1,6-bisphosphatase from turkey liver (1975), Arch. Biochem. Biophys., 168, 171-179.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.3.11 EDTA activation Meleagris gallopavo
3.1.3.11 His activation Meleagris gallopavo
3.1.3.11 His D-His and L-His activate equally Meleagris gallopavo

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.11 AMP sensitivity to AMP is decreased with increase in pH, temperature and Mg2+ concentration Meleagris gallopavo
3.1.3.11 fructose 1,6-diphosphate above 0.015 mM Meleagris gallopavo
3.1.3.11 Mg2+ above 1.5 mM Meleagris gallopavo
3.1.3.11 Mn2+ above 0.075 mM Meleagris gallopavo

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.3.11 Mg2+ optimal concentration: 1-1.5 mM Meleagris gallopavo
3.1.3.11 Mg2+ divalent cation required. Mn2+ or Mg2+ Meleagris gallopavo
3.1.3.11 Mn2+ divalent cation required. Mn2+ or Mg2+ Meleagris gallopavo
3.1.3.11 Mn2+ Mn2+ is significantly more effective than Mg2+ Meleagris gallopavo
3.1.3.11 Mn2+ optimal concentration: 0.05-0.075 mM Meleagris gallopavo

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.11 Meleagris gallopavo
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.3.11
-
Meleagris gallopavo

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.11 kidney
-
Meleagris gallopavo
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.3.11 6.9
-
pH 9.2 Meleagris gallopavo
3.1.3.11 18.05
-
pH 7.5 Meleagris gallopavo

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.11 D-fructose 1,6-diphosphate + H2O
-
Meleagris gallopavo D-fructose 6-phosphate + phosphate
-
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pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.3.11 7.3 7.7 in presence of His, at 42°C Meleagris gallopavo
3.1.3.11 7.5 7.7 in presence of His, at 30°C Meleagris gallopavo
3.1.3.11 8.3 8.5 at 30°C and at 42°C Meleagris gallopavo