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Literature summary extracted from

  • Tejwani, G.A.; Pedrosa, F.O.; Pontremoli, S.; Horecker, B.L.
    The purification of properties of rat liver fructose 1,6-bisphosphatase (1976), Arch. Biochem. Biophys., 177, 255-264.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.3.11 NH4+
-
 Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.11 AMP
-
 Rattus norvegicus
3.1.3.11 Ca2+ competitive with respect to Mg2+ Rattus norvegicus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.3.11 Mg2+ divalent cation required. Mn2+ or Mg2+ Rattus norvegicus
3.1.3.11 Mn2+ divalent cation required. Mn2+ or Mg2+ Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.3.11 140000
-
 sucrose density gradient centrifugation Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.11 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.3.11
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.11 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.3.11 29
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.11 D-fructose 1,6-diphosphate + H2O
-
 Rattus norvegicus D-fructose 6-phosphate + phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.3.11 tetramer 4 * 38000-39000, SDS-PAGE Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.3.11 7
-
 in presence of 0.1 mM EDTA Rattus norvegicus
3.1.3.11 8
-
 in presence of 2 mM MgCl2 Rattus norvegicus