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Literature summary extracted from

  • Marcus, F.; Rittenhouse, J.; Chatterjee, T.; Hosey, M.M.
    Fructose-1,6-bisphosphatase from rat liver (1982), Methods Enzymol., 90, 352-357.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.3.11 EDTA activation Rattus norvegicus
3.1.3.11 fructose 1,6-diphosphate substrate inhibition Rattus norvegicus
3.1.3.11 His activation Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.11 AMP
-
 Rattus norvegicus
3.1.3.11 Fe2+
-
 Rattus norvegicus
3.1.3.11 Fe3+
-
 Rattus norvegicus
3.1.3.11 fructose 2,6-diphosphate
-
 Rattus norvegicus
3.1.3.11 Li+
-
 Rattus norvegicus
3.1.3.11 Zn2+ due to binding to a noncatalytic divalent metal binding site Rattus norvegicus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.3.11 K+ activates Rattus norvegicus
3.1.3.11 Mg2+ divalent cation required. Mn2+ or Mg2+ Rattus norvegicus
3.1.3.11 Mn2+ divalent cation required. Mn2+ or Mg2+ Rattus norvegicus
3.1.3.11 Na+ activates Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.3.11 42000
-
 x * 42000, SDS-PAGE Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.11 Rattus norvegicus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.1.3.11 side-chain modification the enzyme can be phosphorylated by the catalytic subunit of cyclic AMP-dependent protein kinase Rattus norvegicus

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.3.11
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.11 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.3.11 34
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.11 D-fructose 1,6-diphosphate + H2O
-
 Rattus norvegicus D-fructose 6-phosphate + phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.3.11 ? x * 42000, SDS-PAGE Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.3.11 7 7.5
-
 Rattus norvegicus