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Literature summary extracted from

  • Robinson, M.; Blank, M.L.; Snyder, F.
    Acylation of lysophospholipids by rabbit alveolar macrophages (1985), J. Biol. Chem., 260, 7889-7895.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.148 membrane
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 Oryctolagus cuniculus 16020
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Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.147 additional information Oryctolagus cuniculus the reaction is extremely important in the remodeling of phospholipid molecular species and the mobilization of arachidonate into ether-linked lipids. The transfer of arachidonate to 1-alkyl-2-lyso-sn-glycero-3-phosphocholine is important in the final inactivation step for platelet activating factor (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine), whereby 1-alkyl-2-arachidonoyl-sn-glycerol-3-phosphocholine, a stored precursor of both platelet activating factor and arachidonic acid metabolites is formed ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.147 Oryctolagus cuniculus
-
-
-
2.3.1.148 Oryctolagus cuniculus
-
-
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.147 alveolar macrophage
-
 Oryctolagus cuniculus
-
2.3.1.148 alveolar macrophage
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 Oryctolagus cuniculus
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.147 additional information specific for arachidonate Oryctolagus cuniculus ?
-
 ?
2.3.1.147 additional information the reaction is extremely important in the remodeling of phospholipid molecular species and the mobilization of arachidonate into ether-linked lipids. The transfer of arachidonate to 1-alkyl-2-lyso-sn-glycero-3-phosphocholine is important in the final inactivation step for platelet activating factor (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine), whereby 1-alkyl-2-arachidonoyl-sn-glycerol-3-phosphocholine, a stored precursor of both platelet activating factor and arachidonic acid metabolites is formed Oryctolagus cuniculus ?
-
 ?
2.3.1.148 1-Alkyl-2-lyso-sn-glycero-3-phosphocholine + phospholipid
-
 Oryctolagus cuniculus ?
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
2.3.1.148 CoA required Oryctolagus cuniculus