EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
6.3.4.4 | R147L | mutant R147L shows increased Km for IMP and GTP relative to the wild-type enzyme, Km for Asp exhibits a modest decrease | Escherichia coli |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
6.3.4.4 | Phenylglyoxal | GTP or IMP partially protect | Escherichia coli |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
6.3.4.4 | 0.022 | - |
GTP | wild-type | Escherichia coli | |
6.3.4.4 | 0.024 | - |
IMP | wild-type | Escherichia coli | |
6.3.4.4 | 0.115 | - |
Asp | mutant R147L | Escherichia coli | |
6.3.4.4 | 0.118 | - |
IMP | mutant R147L | Escherichia coli | |
6.3.4.4 | 0.133 | - |
GTP | mutant R147L | Escherichia coli | |
6.3.4.4 | 0.191 | - |
Asp | wild-type | Escherichia coli |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.3.4.4 | Escherichia coli | - |
wild-type and mutant R147L | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.3.4.4 | GTP + IMP + L-Asp | - |
Escherichia coli | GDP + phosphate + adenylosuccinate | - |
? |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
6.3.4.4 | additional information | - |
additional information | - |
Escherichia coli |