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Literature summary extracted from
- Characteriation of hydrosoluble and detergent-solubilized forms of mitochondrial NAD+ glycohydrolase from bovine liver (1997), Adv. Exp. Med. Biol., 419, 447-451.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.2.2.5 | EDTA | detergent solubilized NADase, not the steapsin treated enzyme | Bos taurus |  |
| 3.2.2.5 | NaCl | - |
Bos taurus | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.2.2.5 | 0.009 | - |
epsilon-NAD+ | steapsin treated enzyme | Bos taurus | |
| 3.2.2.5 | 0.01 | - |
epsilon-NAD+ | detergent solubilized NADase | Bos taurus | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.2.2.5 | mitochondrion | - |
Bos taurus | 5739 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.2.2.5 | Zn2+ | bivalent cations for example Zn2+, not Mg2+ | Bos taurus | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.2.2.5 | NAD+ + H2O | Bos taurus | - |
ADPribose + nicotinamide | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.2.2.5 | Bos taurus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.2.2.5 | - |
Bos taurus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.2.2.5 | spleen | - |
Bos taurus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.2.2.5 | epsilon-NAD+ + H2O | - |
Bos taurus | ADP-D-ribose + nicotinamide | - |
? | |
| 3.2.2.5 | NAD+ + H2O | - |
Bos taurus | ADPribose + nicotinamide | - |
? | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.2.2.5 | 36 | - |
steapsin treated enzyme | Bos taurus |
| 3.2.2.5 | 39 | - |
detergent solubilized NADase | Bos taurus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.2.2.5 | 8.3 | - |
detergent solubilized NADase | Bos taurus |
| 3.2.2.5 | 8.5 | - |
steapsin treated enzyme | Bos taurus |
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Release 2023.1 (January 2023)
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