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Literature summary extracted from

  • Atsumi, S.; Nosaka, C.; Iinuma, H.; Umezawa, K.
    Inhibition of glucocerebrosidase and induction of neural abnormality by cyclophellitol in mice (1992), Arch. Biochem. Biophys., 297, 362-367.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.45 cyclophellitol oral application induces Gaucher like disease Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.2.1.45 glucocerebroside + H2O Mus musculus
-
 glucose + ceramide
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.45 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.45 brain
-
 Mus musculus
-
3.2.1.45 kidney
-
 Mus musculus
-
3.2.1.45 liver
-
 Mus musculus
-
3.2.1.45 muscle
-
 Mus musculus
-
3.2.1.45 spleen
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.45 4-methylumbelliferyl-beta-D-glucopyranoside + H2O
-
 Mus musculus methylumbelliferone + glucose
-
 ?
3.2.1.45 glucocerebroside + H2O
-
 Mus musculus glucose + ceramide
-
 ?
3.2.1.45 N-stearoylglucosyl ceramide + H2O
-
 Mus musculus D-glucose + stearoylceramide
-
 ?