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Literature summary extracted from

  • Shafit-Zagardo, B.; Turner, B.M.
    Human beta-glucosidase: inhibition by sulphates and purification by affinity chromatography on Dextran-sulphate-Sepharose (1981), Biochim. Biophys. Acta, 659, 7-14.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.2.1.45 phosphatidylglycerol
-
 Homo sapiens

General Stability

EC Number General Stability Organism
3.2.1.45 phospholipid, preincubation stabilizes Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.45 chondroitin sulfate
-
 Homo sapiens
3.2.1.45 Dextran sulfate
-
 Homo sapiens
3.2.1.45 SO42-
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.2.1.45 glucocerebroside + H2O Homo sapiens
-
 glucose + ceramide
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.45 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.2.1.45
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.45 placenta
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.2.1.45 3.57
-
-
 Homo sapiens

Storage Stability

EC Number Storage Stability Organism
3.2.1.45 -20°C, 25% glycerol, several months, no loss of activity Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.45 4-methylumbelliferyl-beta-D-glucopyranoside + H2O
-
 Homo sapiens methylumbelliferone + glucose
-
 ?
3.2.1.45 glucocerebroside + H2O
-
 Homo sapiens glucose + ceramide
-
 ?
3.2.1.45 N-stearoyl-dihydroglucocerebroside + H2O
-
 Homo sapiens D-glucose + N-stearoyl-dihydrocerebroside
-
 ?