Literature summary extracted from

Spector, T.; Beacham III, L.M.
Guanosine monophosphate synthetase from Escherichia coli B-96. Inhibition by nucleosides (1975), J. Biol. Chem., 250, 3101-3107.

Inhibitors

EC Number	Inhibitors	Comment	Organism
6.3.5.2	1,N6-Ethenoadenosine	-	Escherichia coli
6.3.5.2	1-methyladenosine	-	Escherichia coli
6.3.5.2	2'-deoxyadenosine	-	Escherichia coli
6.3.5.2	2,6-diaminopurine ribonucleoside	-	Escherichia coli
6.3.5.2	2-Amino-6-methylthiopurine ribonucleoside	-	Escherichia coli
6.3.5.2	2-fluoroadenosine	-	Escherichia coli
6.3.5.2	3'-deoxyadenosine	-	Escherichia coli
6.3.5.2	5'-Azido-5'-deoxyadenosine	-	Escherichia coli
6.3.5.2	5'-thioethyl-5'-deoxyadenosine	-	Escherichia coli
6.3.5.2	6-Chloropurine ribonucleoside	-	Escherichia coli
6.3.5.2	6-Methylmercaptopurine ribonucleoside	-	Escherichia coli
6.3.5.2	6-Methylpurine ribonucleoside	-	Escherichia coli
6.3.5.2	6-Methylpurine ribonucleotide	-	Escherichia coli
6.3.5.2	8-azaadenosine	-	Escherichia coli
6.3.5.2	8-Bromoadenosine	-	Escherichia coli
6.3.5.2	adenine arabinoside	-	Escherichia coli
6.3.5.2	adenosine	-	Escherichia coli
6.3.5.2	ADP	-	Escherichia coli
6.3.5.2	Decoyinine	-	Escherichia coli
6.3.5.2	diphosphate	competitive with respect to ATP; kinetic parameters for the two progressively formed inhibitory complexes	Escherichia coli
6.3.5.2	Glucofuranosyladenine	-	Escherichia coli
6.3.5.2	kinetin ribonucleoside	-	Escherichia coli
6.3.5.2	mycophenolate	-	Escherichia coli
6.3.5.2	N6,N6-Dimethyladenosine	-	Escherichia coli
6.3.5.2	N6-Allyladenosine	-	Escherichia coli
6.3.5.2	N6-Benzyladenosine	-	Escherichia coli
6.3.5.2	N6-Hydroxyaminopurine ribonucleoside	-	Escherichia coli
6.3.5.2	N6-isopentenyladenosine	-	Escherichia coli
6.3.5.2	N6-methyladenosine	-	Escherichia coli
6.3.5.2	Nucleodide inhibitors	overview	Escherichia coli
6.3.5.2	tubercidin	-	Escherichia coli
6.3.5.2	zeatin ribonucleoside	-	Escherichia coli

Organism

EC Number	Organism	UniProt	Comment	Textmining
6.3.5.2	Escherichia coli	-	-	-
6.3.5.2	Escherichia coli B96	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
6.3.5.2	ATP + XMP + NH4+	-	Escherichia coli	AMP + diphosphate + GMP	-	?
6.3.5.2	ATP + XMP + NH4+	-	Escherichia coli B96	AMP + diphosphate + GMP	-	?