Literature summary extracted from

  • Spector, T.; Beacham III, L.M.
    Guanosine monophosphate synthetase from Escherichia coli B-96. Inhibition by nucleosides (1975), J. Biol. Chem., 250, 3101-3107.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.3.5.2 1-methyladenosine
-
Escherichia coli
6.3.5.2 1,N6-Ethenoadenosine
-
Escherichia coli
6.3.5.2 2,6-diaminopurine ribonucleoside
-
Escherichia coli
6.3.5.2 2-Amino-6-methylthiopurine ribonucleoside
-
Escherichia coli
6.3.5.2 2'-deoxyadenosine
-
Escherichia coli
6.3.5.2 2-fluoroadenosine
-
Escherichia coli
6.3.5.2 3'-deoxyadenosine
-
Escherichia coli
6.3.5.2 5'-Azido-5'-deoxyadenosine
-
Escherichia coli
6.3.5.2 5'-thioethyl-5'-deoxyadenosine
-
Escherichia coli
6.3.5.2 6-Chloropurine ribonucleoside
-
Escherichia coli
6.3.5.2 6-Methylmercaptopurine ribonucleoside
-
Escherichia coli
6.3.5.2 6-Methylpurine ribonucleoside
-
Escherichia coli
6.3.5.2 6-Methylpurine ribonucleotide
-
Escherichia coli
6.3.5.2 8-azaadenosine
-
Escherichia coli
6.3.5.2 8-Bromoadenosine
-
Escherichia coli
6.3.5.2 adenine arabinoside
-
Escherichia coli
6.3.5.2 adenosine
-
Escherichia coli
6.3.5.2 ADP
-
Escherichia coli
6.3.5.2 Decoyinine
-
Escherichia coli
6.3.5.2 diphosphate competitive with respect to ATP; kinetic parameters for the two progressively formed inhibitory complexes Escherichia coli
6.3.5.2 Glucofuranosyladenine
-
Escherichia coli
6.3.5.2 kinetin ribonucleoside
-
Escherichia coli
6.3.5.2 mycophenolate
-
Escherichia coli
6.3.5.2 N6-Allyladenosine
-
Escherichia coli
6.3.5.2 N6-Benzyladenosine
-
Escherichia coli
6.3.5.2 N6-Hydroxyaminopurine ribonucleoside
-
Escherichia coli
6.3.5.2 N6-isopentenyladenosine
-
Escherichia coli
6.3.5.2 N6-methyladenosine
-
Escherichia coli
6.3.5.2 N6,N6-Dimethyladenosine
-
Escherichia coli
6.3.5.2 Nucleodide inhibitors overview Escherichia coli
6.3.5.2 tubercidin
-
Escherichia coli
6.3.5.2 zeatin ribonucleoside
-
Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
6.3.5.2 Escherichia coli
-
-
-
6.3.5.2 Escherichia coli B96
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.5.2 ATP + XMP + NH4+
-
Escherichia coli AMP + diphosphate + GMP
-
?
6.3.5.2 ATP + XMP + NH4+
-
Escherichia coli B96 AMP + diphosphate + GMP
-
?