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Literature summary extracted from
- Purification and comparison of the structures of human liver acidic alpha-D-mannosidases A and B (1986), Biochem. J., 233, 65-72.
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.2.1.24 | 26000 | - |
alpha3beta3, 3 * 62000 + 3 * 26000, SDS-PAGE, alpha-mannosidase A | Homo sapiens |
| 3.2.1.24 | 62000 | - |
alpha3beta3, 3 * 62000 + 3 * 26000, SDS-PAGE, alpha-mannosidase A | Homo sapiens |
| 3.2.1.24 | 260000 | - |
alpha-mannosidase B | Homo sapiens |
| 3.2.1.24 | 280000 | - |
gel filtration, alpha-mannosidase A | Homo sapiens |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.2.1.24 | Homo sapiens | - |
2 isoforms, alpha-mannosidase A, B | - |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 3.2.1.24 | glycoprotein | - |
Homo sapiens |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.2.1.24 | to homogeneity, chromatography steps | Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.2.1.24 | liver | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.2.1.24 | 2.5 | - |
alpha-mannosidase A | Homo sapiens |
| 3.2.1.24 | 4.6 | - |
alpha-mannosidase B | Homo sapiens |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.2.1.24 | 4-methylumbelliferyl-alpha-D-mannopyranoside + H2O | - |
Homo sapiens | 4-methylumbelliferone + alpha-D-mannopyranose | - |
? |  |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.2.1.24 | hexamer | alpha3beta3, 3 * 62000 + 3 * 26000, SDS-PAGE, alpha-mannosidase A | Homo sapiens |
| 3.2.1.24 | oligomer | composed of equal amounts of 62, 58 and 26 kDa subunits | Homo sapiens |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.2.1.24 | acid alpha-mannosidase | - |
Homo sapiens |
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