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Literature summary extracted from

  • Richter, D.
    In vitro degradation of guanosine 3,5-bis(diphosphate) [ppGpp] by the spoT gene product [ppGppase] from auxotrophic strains of Escherichia coli: effects of various antibiotics and drugs (1980), Arch. Microbiol., 124, 229-232.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.7.2 chlorotetracycline
-
Escherichia coli
3.1.7.2 Levallorphan
-
Escherichia coli
3.1.7.2 tetracycline
-
Escherichia coli
3.1.7.2 Thiostrepton
-
Escherichia coli

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.7.2 Mn2+ activation Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.7.2 ppGpp + H2O Escherichia coli
-
ppG + diphosphate
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.1.7.2 Escherichia coli
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.7.2 ppGpp + H2O
-
Escherichia coli ppG + diphosphate
-
?
3.1.7.2 ppGpp + H2O i.e. guanosine-3',5'-bis(diphosphate) Escherichia coli ppG + diphosphate i.e. guanosine 5'-diphosphate ?