Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Shankaran, R.; Ameen, M.; Daniel, W.L.; Davidson, R.G.; Chang, P.L.
    Characterization of arylsulfatase C isozymes from human liver and placenta (1991), Biochim. Biophys. Acta, 1078, 251-257.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.6.2 0.27
-
 methylumbelliferyl sulfate s-form Homo sapiens
3.1.6.2 0.58
-
 methylumbelliferyl sulfate f-form Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.6.2 183000
-
 placenta, s-form, gel filtration, two isoforms s- and f-form Homo sapiens
3.1.6.2 200000
-
 liver, f-form, gel filtration, two isoforms s- and f-form Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.6.2 steroid sulfates + H2O Homo sapiens also acts on some related steryl sulfates, phenol sulfates, steroid arylsulfates and steroid alkyl sulfates catalyzed at the same site steroid + sulfate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.6.2 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.6.2
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.6.2 liver
-
 Homo sapiens
-
3.1.6.2 placenta
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.6.2 4-methylumbelliferyl sulfate + H2O both s-form and f-form Homo sapiens 4-methylumbelliferone + sulfate
-
 ?
3.1.6.2 cholesterol 3-sulfate + H2O only s-form Homo sapiens cholesterol + sulfate
-
 ?
3.1.6.2 dehydroepiandrosterone 3-sulfate + H2O only s-form Homo sapiens dehydroepiandrosterone + sulfate
-
 ?
3.1.6.2 estrone sulfate + H2O only s-form Homo sapiens estrone + sulfate
-
 ?
3.1.6.2 steroid sulfates + H2O also acts on some related steryl sulfates, phenol sulfates, steroid arylsulfates and steroid alkyl sulfates catalyzed at the same site Homo sapiens steroid + sulfate
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.1.6.2 50
-
 f-form: 50% loss of activity Homo sapiens
3.1.6.2 57
-
 s-form: 50% loss of activity Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.6.2 5 5.5
-
 Homo sapiens
3.1.6.2 6.9
-
 f-form Homo sapiens
3.1.6.2 7.3 7.5
-
 Homo sapiens