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Literature summary extracted from

  • Pannbacker, R.G.; Fleischman, D.E.; Reed, D.W.
    Cyclic nucleotide phosphodiesterase: high activity in a mammalian photoreceptor (1972), Science, 175, 757-758.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.4.17 Ca2+
-
 Bos taurus
3.1.4.17 Caffeine
-
 Bos taurus
3.1.4.17 dibutyryl cyclic AMP
-
 Bos taurus
3.1.4.17 papaverine
-
 Bos taurus
3.1.4.17 theophylline
-
 Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.4.17 7
-
 3',5'-cAMP
-
 Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.4.17 photoreceptor outer segment rod outer segment Bos taurus 1750
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.4.17 Mg2+ required Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.17 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.4.17 6fold Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.4.17 photoreceptor
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.17 3',5'-cAMP + H2O
-
 Bos taurus 5'-AMP
-
 ?
3.1.4.17 3',5'-cGMP + H2O
-
 Bos taurus 5'-GMP
-
 ?
3.1.4.17 nucleoside 3',5'-cyclic phosphate + H2O
-
 Bos taurus nucleoside 5'-phosphate
-
 ?