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Literature summary extracted from

  • Hansen, R.S.; Charbonneau, H.; Beavo, J.A.
    Purification of calmodulin-stimulated cyclic nucleotide phosphodiesterase by monoclonal antibody affinity chromatography (1988), Methods Enzymol., 159, 543-557.
    View publication on PubMed

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.4.17 Ca2+
-
 Rattus norvegicus
3.1.4.17 Ca2+
-
 Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.17 Bos taurus
-
-
-
3.1.4.17 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.4.17 3700fold Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.4.17 brain
-
 Rattus norvegicus
-
3.1.4.17 brain
-
 Bos taurus
-
3.1.4.17 heart
-
 Rattus norvegicus
-
3.1.4.17 heart
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.4.17 additional information
-
-
 Rattus norvegicus
3.1.4.17 additional information
-
-
 Bos taurus

Storage Stability

EC Number Storage Stability Organism
3.1.4.17 4-7°C, 40% glycerol, 0.00015 mM NaCl, stable for at least 1 year Bos taurus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.17 3',5'-cAMP + H2O
-
 Rattus norvegicus 5'-AMP
-
 ?
3.1.4.17 3',5'-cAMP + H2O
-
 Bos taurus 5'-AMP
-
 ?
3.1.4.17 3',5'-cGMP + H2O
-
 Rattus norvegicus 5'-GMP
-
 ?
3.1.4.17 3',5'-cGMP + H2O
-
 Bos taurus 5'-GMP
-
 ?
3.1.4.17 nucleoside 3',5'-cyclic phosphate + H2O
-
 Rattus norvegicus nucleoside 5'-phosphate
-
 ?
3.1.4.17 nucleoside 3',5'-cyclic phosphate + H2O
-
 Bos taurus nucleoside 5'-phosphate
-
 ?