BRENDA - Enzyme Database

Pulmonary phosphatidic acid phosphatase. A comparative study of the aqueously dispersed phosphatidate-dependent and membrane-bound phosphatidate-dependent phosphatidic acid phosphatase activities of rat lung

Yeung, A.; Casola, P.G.; Wong, C.; Fellows, J.F.; Possmayer, F.; Biochim. Biophys. Acta 574, 226-239 (1979)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.3.4
Ca2+
activity with aqueously dispersed phosphatidic acid
Rattus norvegicus
3.1.3.4
F-
activity with aqueously dispersed phosphatidic acid
Rattus norvegicus
3.1.3.4
Mg2+
at high concentrations, activity with aqueously dispersed phosphatidic acid
Rattus norvegicus
3.1.3.4
Mn2+
activity with aqueously dispersed phosphatidic acid
Rattus norvegicus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
3.1.3.4
cytosol
-
Rattus norvegicus
5829
-
3.1.3.4
microsome
-
Rattus norvegicus
-
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.1.3.4
Rattus norvegicus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.3.4
lung
-
Rattus norvegicus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.3.4
phosphatidic acid + H2O
-
134873
Rattus norvegicus
1,2-diacyl-sn-glycerol + phosphate
-
-
-
?
pH Optimum
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
3.1.3.4
6
6.5
and the major activity peak at pH 7.5-8.0, aqueously dispersed phosphatidic acid, cytosolic activity
Rattus norvegicus
3.1.3.4
6.5
7.5
membrane-bound phosphatidic acid, microsomal enzyme
Rattus norvegicus
3.1.3.4
6.5
-
and a minor peak of activity at pH 7.5-8, aqueously dispersed phosphatidic acid, microsomal enzyme
Rattus norvegicus
3.1.3.4
7.4
8
membrane-bound phosphatidic acid, cytosolic enzyme
Rattus norvegicus
3.1.3.4
7.5
8
and a distinct optimum at pH 6.0-6.5, aqueously dispersed phosphatidic acid, cytosolic enzyme
Rattus norvegicus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.3.4
Ca2+
activity with aqueously dispersed phosphatidic acid
Rattus norvegicus
3.1.3.4
F-
activity with aqueously dispersed phosphatidic acid
Rattus norvegicus
3.1.3.4
Mg2+
at high concentrations, activity with aqueously dispersed phosphatidic acid
Rattus norvegicus
3.1.3.4
Mn2+
activity with aqueously dispersed phosphatidic acid
Rattus norvegicus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
3.1.3.4
cytosol
-
Rattus norvegicus
5829
-
3.1.3.4
microsome
-
Rattus norvegicus
-
-
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.3.4
lung
-
Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.3.4
phosphatidic acid + H2O
-
134873
Rattus norvegicus
1,2-diacyl-sn-glycerol + phosphate
-
-
-
?
pH Optimum (protein specific)
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
3.1.3.4
6
6.5
and the major activity peak at pH 7.5-8.0, aqueously dispersed phosphatidic acid, cytosolic activity
Rattus norvegicus
3.1.3.4
6.5
7.5
membrane-bound phosphatidic acid, microsomal enzyme
Rattus norvegicus
3.1.3.4
6.5
-
and a minor peak of activity at pH 7.5-8, aqueously dispersed phosphatidic acid, microsomal enzyme
Rattus norvegicus
3.1.3.4
7.4
8
membrane-bound phosphatidic acid, cytosolic enzyme
Rattus norvegicus
3.1.3.4
7.5
8
and a distinct optimum at pH 6.0-6.5, aqueously dispersed phosphatidic acid, cytosolic enzyme
Rattus norvegicus