BRENDA - Enzyme Database

Activation of rat liver cytosolic phosphatidic acid phosphatase by nucleoside diphosphates

Berglund, L.; Bj÷rkhem, I.; Angelin, B.; Einarsson, K.; Biochim. Biophys. Acta 1002, 382-387 (1989)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
3.1.3.4
ADP
half-maximal stimulation at 0.2 mM
Rattus norvegicus
3.1.3.4
CDP
stimulates
Rattus norvegicus
3.1.3.4
GDP
stimulates
Rattus norvegicus
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.3.4
ATP
half-maximal inhibition at 0.2 mM
Rattus norvegicus
3.1.3.4
CTP
-
Rattus norvegicus
3.1.3.4
GTP
-
Rattus norvegicus
KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
3.1.3.4
0.67
-
phosphatidic acid
without ATP
Rattus norvegicus
3.1.3.4
1.2
-
phosphatidic acid
in presence of 2 mM ATP
Rattus norvegicus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
3.1.3.4
cytosol
-
Rattus norvegicus
5829
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.1.3.4
Rattus norvegicus
-
-
-
Purification (Commentary)
EC Number
Commentary
Organism
3.1.3.4
-
Rattus norvegicus
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.3.4
liver
-
Rattus norvegicus
-
Specific Activity [micromol/min/mg]
EC Number
Specific Activity Minimum [Ámol/min/mg]
Specific Activity Maximum [Ámol/min/mg]
Commentary
Organism
3.1.3.4
additional information
-
-
Rattus norvegicus
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.3.4
phosphatidic acid + H2O
-
134859
Rattus norvegicus
1,2-diacyl-sn-glycerol + phosphate
-
-
-
?
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
3.1.3.4
ADP
half-maximal stimulation at 0.2 mM
Rattus norvegicus
3.1.3.4
CDP
stimulates
Rattus norvegicus
3.1.3.4
GDP
stimulates
Rattus norvegicus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.3.4
ATP
half-maximal inhibition at 0.2 mM
Rattus norvegicus
3.1.3.4
CTP
-
Rattus norvegicus
3.1.3.4
GTP
-
Rattus norvegicus
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
3.1.3.4
0.67
-
phosphatidic acid
without ATP
Rattus norvegicus
3.1.3.4
1.2
-
phosphatidic acid
in presence of 2 mM ATP
Rattus norvegicus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
3.1.3.4
cytosol
-
Rattus norvegicus
5829
-
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
3.1.3.4
-
Rattus norvegicus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.3.4
liver
-
Rattus norvegicus
-
Specific Activity [micromol/min/mg] (protein specific)
EC Number
Specific Activity Minimum [Ámol/min/mg]
Specific Activity Maximum [Ámol/min/mg]
Commentary
Organism
3.1.3.4
additional information
-
-
Rattus norvegicus
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.3.4
phosphatidic acid + H2O
-
134859
Rattus norvegicus
1,2-diacyl-sn-glycerol + phosphate
-
-
-
?