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Literature summary extracted from
- Chemical structures of pancreatic ribonuclease and deoxyribonuclease (1973), Science, 180, 458-464.
Crystallization (Commentary)
| EC Number | Crystallization (Comment) | Organism |
|---|---|---|
| 4.6.1.18 | purification | Bos taurus |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 4.6.1.18 | 13680 | - |
pancreas, amino acid composition | Bos taurus |
| 4.6.1.18 | 13683 | - |
1 * 13683, pancreas | Bos taurus |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.6.1.18 | RNA + H2O | Bos taurus | endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides ending in Cp or Up with 2',3'-cyclic phosphate intermediates, e.g. tRNA, 18S and 28S rRNA, yeast RNA,4.5S RNA | 3'-phosphomononucleotides + 3'-phosphooligonucleotides | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.6.1.18 | Bos taurus | - |
- |
- |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 4.6.1.18 | glycoprotein | - |
Bos taurus |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 4.6.1.18 | - |
Bos taurus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.6.1.18 | cyclic 2',3'-nucleoside monophosphate + H2O | second step of hydrolysis is irreversible | Bos taurus | 3'-phosphomononucleotides | - |
ir | |
| 4.6.1.18 | RNA + H2O | endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides ending in Cp or Up with 2',3'-cyclic phosphate intermediates, e.g. tRNA, 18S and 28S rRNA, yeast RNA,4.5S RNA | Bos taurus | 3'-phosphomononucleotides + 3'-phosphooligonucleotides | - |
? | |
| 4.6.1.18 | RNA + H2O | first step of hydrolysis is reversible | Bos taurus | cyclic 2',3'-nucleoside monophosphate | - |
r | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 4.6.1.18 | monomer | 1 * 13683, pancreas | Bos taurus |
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Release 2023.1 (January 2023)
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