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Literature summary extracted from

  • Cook, K.G.; Colbran, R.J.; Yeaman, S.J.
    The identity of the cholesteryl ester hydrolase of bovine corpus luteum (1983), Biochem. Soc. Trans., 11, 703.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.1.13 cAMP-dependent protein kinase type II 2fold activation in presence of ATP Bos taurus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.13 diisopropylfluorophosphate
-
 Bos taurus
3.1.1.13 Hg2+
-
 Bos taurus
3.1.1.13 NaF
-
 Bos taurus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.1.13 Mg2+ activation in a reaction mixture containing cAMP, protein kinase A and ATP Bos taurus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.1.13 84000
-
 SDS-PAGE Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.13 cholesteryl esters + H2O Bos taurus important rate-limiting step in steroidogenesis cholesterol + fatty acid
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.13 Bos taurus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.1.1.13 side-chain modification phosphoprotein Bos taurus

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.1.13 partial by chromatography techniques Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.13 corpus luteum
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.1.13 0.34
-
-
 Bos taurus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.13 cholesteryl esters + H2O important rate-limiting step in steroidogenesis Bos taurus cholesterol + fatty acid
-
 ?
3.1.1.13 cholesteryl oleate + H2O
-
 Bos taurus cholesterol + oleic acid
-
 ?
3.1.1.13 triolein + H2O
-
 Bos taurus dioleoylglycerol + oleic acid
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.1.13 monomer 1 * 84000, SDS-PAGE Bos taurus

Cofactor

EC Number Cofactor Comment Organism Structure
3.1.1.13 MgATP2- increasing activity with addition of cAMP-dependend protein kinase Bos taurus